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Acute Posttraumatic Osteomyelitis in Patients With High-energy Tibial Fractures and Biomarkers

NCT03459261 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 86

Last updated 2018-03-09

No results posted yet for this study

Summary

The present trial was aimed to identify which biomarkers could be associated in perioperative period after surgical treatment of tibial fracture to the development of POM.

Conditions

  • Osteomyelitis Tibia
  • Surgical Site Infection

Interventions

DIAGNOSTIC_TEST

blood sample on admission (ADD), first postoperative day (POD1) and fourth postoperative day (POD4)

Laboratory analyses of peripheral venous blood on admission (blood sample ADD), 24 hours after surgery (blood sample POD1) and fourth-day after surgery (blood sample POD4) included biochemical analysis, complete blood count, C-reactive protein (CPR), procalcitonin (PCT), albumin/protein level, prothrombin time and international normalized ratio (INR) (only on admission) and for determination of cytokines: tumor necrosis factor alpha (TFN-α), interleukin-6 (IL-6), interleukin-10 (IL-10).

Sponsors & Collaborators

  • Prof. Alojz Ihan, MD, Ph.D, Institute of Microbiology and Immunology, Ljubljana, Slovenia

    collaborator UNKNOWN

  • University Medical Centre Ljubljana

    lead OTHER

Eligibility

Min Age
15 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-01-01
Primary Completion
2013-12-31
Completion
2014-01-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03459261 on ClinicalTrials.gov