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Passive Leg Raising - an Important Diagnostic Manoeuvre

NCT03454802 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 11

Last updated 2021-09-24

No results posted yet for this study

Summary

The aim is to describe the physiological background for PLR and the interpretation of a PLR manoeuvre.

The protocol entails the measurement of stroke volume (SV) at baseline (semirecumbent patient position), during PLR and after returning to semirecumbent position. Simultaneously blood pressure (BP), pulse rate (PR), pulse oximetric saturation (SpO2) and ECG are recorded. The procedure is performed in ten normal subjects, ten patients recruited in the cardiology outpatient department and ten critically ill patients under analgosedation in the ICU.

Analysis includes changes in measured variables and heart rate variability in the frequency domain during the three phases of the experiment.

Conditions

  • Cardiovascular Insufficiency

Interventions

DIAGNOSTIC_TEST

Passive Leg Raising

See above

Sponsors & Collaborators

  • Edwards Lifesciences

    collaborator INDUSTRY

  • Region MidtJylland Denmark

    lead OTHER

Principal Investigators

  • Peter Toft, MD · Head of Centre of Planned Surgery, Silkeborg Regional Hospital

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-09-01
Primary Completion
2020-10-01
Completion
2020-10-01
FDA Device
Yes

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03454802 on ClinicalTrials.gov