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Different Effects of Non-calcium Phosphate Binders on Serum Calcium

NCT03451019 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2021-07-27

No results posted yet for this study

Summary

Sevelamer hydrochloride (SE) can increase intestinal calcium absorption in contrast to lanthanum carbonate (LA). Study compared effect of LA and SE on serum and urine phosphate and calcium, and hormones regulating mineral-bone metabolism.

Conditions

Interventions

DRUG

Sevelamer Hydrochloride

Single oral doses of lanthanum (1000 mg) or Sevelamer (2400 mg) were administered in random order 15 minutes after 5 g calcium carbonate with standardized meal

DRUG

Lanthanum Carbonate

Single oral doses of lanthanum (1000 mg)

Sponsors & Collaborators

  • Shire

    collaborator INDUSTRY

  • Medical University of Lodz

    lead OTHER

Principal Investigators

  • Michal Nowicki, Prof.MD PhD · Medical University of Lodz

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-03-01
Primary Completion
2020-12-15
Completion
2020-12-30

Countries

  • Poland

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03451019 on ClinicalTrials.gov