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Retinal Nerve Fiber Layer Thickness and Cerebrospinal Fluid Aβ/Tau

NCT03447613 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 86

Last updated 2018-11-30

No results posted yet for this study

Summary

To test the hypothesis that retinal nerve fiber layer (RNFL) thickness is correlated with Aβ and Tau concentration of cerebrospinal fluid (CSF) in an older population.

Conditions

  • Alzheimer Disease

Interventions

PROCEDURE

surgery

All participants were scheduled to have elective total hip or knee replacement surgery, ureteroscopic lithotripsy and transurethral resection of the prostate under spinal anesthesia at the Shanghai 10th People's Hospital. After 5 years, the investigaors will follow up the participants including cognitive functions, PET-CT, thickness of Retinal Nerve Fiber Layer.

Sponsors & Collaborators

  • Massachusetts General Hospital

    collaborator OTHER

  • Shanghai 10th People's Hospital

    lead OTHER

Principal Investigators

  • Yuan Shen, MD, PhD · Shanghai 10th People's Hospital

Eligibility

Min Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-08-01
Primary Completion
2014-12-31
Completion
2014-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03447613 on ClinicalTrials.gov