Timeliness of Immunization and Compliance Assessment Study

Summary

Although coverage for primary childhood immunizations has improved, a significant proportion of young children and pregnant women living in low-resource settings remain inadequately immunized. While young children receive some primary vaccines, many are never fully vaccinated. Progressive decline in immunizations are in large part attributable to poor follow-up and compliance. Major challenges include maintaining immunization records linked to positive identification of the individual child, incentivizing follow-up and return immunizations and efficiently identifying and targeting non-compliant subjects. Mobile-phone costs have decreased dramatically in the developing world with rapid proliferation of web and mobile-phone connectivity. Novel approaches that integrate these modern technologies with existing resources in low and middle income countries can cost-effectively address these challenges. In this proposal, investigators will evaluate a novel software platform, utilizing biometric identification and of subjects, paired with intelligent and subject-aware, mobile-phone reminders and compliance-linked incentives to improve uptake and coverage of primary vaccinations in young children.

Conditions

• Vaccinations

Interventions

BEHAVIORAL

Standard Compliance-linked incentives

Standard mobile-phone reminders and compliance-linked incentives Electronic immunization records on cloud-based software platform and use of biometric identification

BEHAVIORAL

Intelligent Compliance-linked incentives

Intelligent mobile-phone reminders and compliance-linked incentives Electronic immunization records on cloud-based software platform and use of biometric identification

OTHER

Record keeping

Electronic immunization records on cloud-based software platform and use of biometric identification

Sponsors & Collaborators

• Bill and Melinda Gates Foundation

  collaborator OTHER

• Bal Umang Drishya Sanstha (BUDS), India

  collaborator OTHER

• Royal Datamatics Pvt. Ltd. (RDPL), India

  collaborator UNKNOWN

• St. Louis University

  collaborator OTHER

• Johns Hopkins University

  lead OTHER

Principal Investigators

• Sanjay K Jain, MD · Johns Hopkins University

Study Design

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

DOUBLE

Model

PARALLEL

Eligibility

Max Age

24 Months

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2018-04-25

Primary Completion

2019-09-25

Completion

2019-09-25

Countries

• India

Study Locations