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Detection of Hypoxia in Human Thoracic Aorta Using Pimonidazole Hydrochloride

NCT03410420 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 9

Last updated 2026-01-23

No results posted yet for this study

Summary

This is a prospective study designed to determine the safety and value of Hypoxyprobe-1 (pimonidazole hydrochloride (-HCl)) to detect levels of tissue hypoxia in patients presenting with ascending aortic aneurysm.

Conditions

  • Aortic Aneurysm, Thoracic

Interventions

DRUG

Pimonidazole hydrochloride

administration of pimonidazole-HCl

Sponsors & Collaborators

  • Thomas Gleason

    lead OTHER

Principal Investigators

  • Thomas G Gleason, MD · University of Pittsburgh

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-09-01
Primary Completion
2025-09-01
Completion
2025-09-01
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03410420 on ClinicalTrials.gov