Pelvic Microbiomes of Benign and Malignant Ovarian Diseases
NCT03388996 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 40
Last updated 2018-11-14
Summary
This case-control study aims to compare the pelvic microbiomes of benign ovarian diseases and ovarian malignancies by 16s RNA techniques and culture. Discharges/flushing fluid from vagina, faces and fimbria end of fallopian tube are collected from age and menopausal status matched patient before and during procedures of laparoscopies. The discharges/flushing fluid would be sent for 16s RNA analysis and microculture respectively, and the results would get self-contrasted comparison and case-control comparison.
Conditions
- Microbiota
- Ovarian Neoplasms
- Ribosome Alteration
Interventions
- DIAGNOSTIC_TEST
-
microbiomes
16s RNA analysis and microculture of discharges/flushing fluid from vagina, faces and fimbria end of fallopian tube
Sponsors & Collaborators
-
Academy Military Medical Science, China
collaborator INDUSTRY -
Lei Li
lead OTHER
Principal Investigators
-
Lei Li, MD · Peking Union Medical College Hospital
Eligibility
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-01-01
- Primary Completion
- 2020-01-01
- Completion
- 2021-01-01
Countries
- China
Study Locations
More Related Trials
-
Vaginal Microbiota and Its Association with Pap Smear Results, Human Papillomavirus, Vitamins, and Metabolic Mark
NCT06897800 ·Status: COMPLETED
-
Lavage of the Uterine Cavity for the Diagnosis of Serous Tubal Intraepithelial Carcinoma
NCT02039388 ·Status: COMPLETED ·Phase: NA
-
Characteristics of Vaginal and Intestinal Microbiota and Cervical HPV Infection
NCT05003505 ·Status: ACTIVE_NOT_RECRUITING
-
Gut Microbiome in Gynecological Cancer Patients With Pelvic Toxicity: Controls Versus Ozone Treatment. (MicrOzoGineTox)
NCT07259681 ·Status: NOT_YET_RECRUITING
-
Collecting Tumor Samples From Patients With Gynecological Tumors
NCT00897442 ·Status: COMPLETED
-
Screening and Identification of Ovarian Cancers
NCT00854399 ·Status: UNKNOWN ·Phase: NA
-
The Effectiveness of Liquid Biopsy in Differential Diagnosis and Early Screening of Epithelial Ovarian Cancer
NCT05931055 ·Status: NOT_YET_RECRUITING
-
A Cohort Study of Uterine Malignancies
NCT05635123 ·Status: RECRUITING
-
DNA Methylation for Screening Uterine Cervical Lesions
NCT03960879 ·Status: UNKNOWN
-
Persistent Cervical HPV Infection With Clearance and Vaginal Microbiota
NCT03895866 ·Status: UNKNOWN
-
Cohort of Patients With Pelvic Gynecological Cancer: Constitution of a Collection of Biological Samples With Radioclinical Characterization
NCT03622983 ·Status: RECRUITING
-
Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer
NCT05051722 ·Status: RECRUITING
-
Screening of Biomarkers on Endometrial Cancers
NCT00674349 ·Status: UNKNOWN ·Phase: NA
-
PERformance of Multi-Cancer Early-detectIon Based on Various Biomarkers in fEmale Cancers, PERCEIVE-II
NCT06001099 ·Status: UNKNOWN
-
DNA Methylation for Screening Uterine Cervical Lesions: A Case-control Study
NCT03961191 ·Status: UNKNOWN
-
Intra-tumor Injection of Oncolytic Viruses H101 Combined With or Without Radiotherapy in Refractory/Recurrent Gynecological Malignancies
NCT05051696 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
The Study of Massively Parallel Sequencing in Early Detection for Gynecologic Malignant Tumor
NCT02166515 ·Status: UNKNOWN
-
A Controlled Study of Quality of Life and it's Related Factors Among Gynecological Cancer Survivors
NCT01187706 ·Status: UNKNOWN
-
Identification and Characterization of Endometrial Cancer With Specific Tumor Markers in Serum and Endometrial Tissue
NCT03498924 ·Status: COMPLETED
-
Cervical Cancer Screening Strategies
NCT05309122 ·Status: UNKNOWN
-
DNA Methylation and the Increased Risk of Cervical Cancer Development
NCT06859151 ·Status: NOT_YET_RECRUITING
-
Gut Microbiome and Treatment for Gynecological Cancer Patients Receiving Immunotherapy
NCT04957511 ·Status: RECRUITING
-
PERformance of Multi-Cancer Early-detectIon Based on Various Biomarkers in fEmale Cancers, PERCEIVE-I
NCT04903665 ·Status: UNKNOWN
-
Oral Antibiotic Bowel Preparation in Gynecologic Oncology Surgery
NCT05210556 ·Status: COMPLETED
-
Lavage of the Uterine Cavity for the Diagnosis of Ovarian and Tubal Carcinoma - Study of Sensitivity and Specificity
NCT02518256 ·Status: COMPLETED ·Phase: NA