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Investigating Bone and Skeletal Muscle Interaction in Men With Prostate Cancer

NCT03386812 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 19

Last updated 2021-01-15

No results posted yet for this study

Summary

The overall goal of this pilot project is to test the hypothesis that a decline in muscle strength precedes the decline in bone strength in men undergoing androgen deprivation therapy (ADT) for prostate cancer. The investigators will measure changes in serum biomarkers involved in muscle-bone crosstalk, anatomic changes in muscle and bone structure and strength that could ultimately contribute to fractures. The findings from this research will inform design of interventions to reduce falls and hip fractures in patients undergoing ADT as well as application to broader populations of at risk patients.

Conditions

Sponsors & Collaborators

  • Charles Y. C. Pak Foundation

    collaborator UNKNOWN

  • University of Texas Southwestern Medical Center

    lead OTHER

Principal Investigators

  • Craig Rubin, MD · UT Southwestern

  • Orhan Oz, MD,PhD · UT Southwestern

Eligibility

Min Age
55 Years
Max Age
89 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-10-01
Primary Completion
2020-11-29
Completion
2020-11-29

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03386812 on ClinicalTrials.gov