A Prospective Study of Molecular Detection of Salvageable Early Recurrent Nasopharyngeal Carcinoma After Radiotherapy
NCT03379610 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 426
Last updated 2021-04-30
Summary
To evaluate the sensitivity and specificity of the combination of EBV and methylation marker genes in body fluids of both plasma and nasopharyngeal brush together for screening of early salvageable local residual and recurrent NPC that are missed by conventional clinical follow-up protocol.
Conditions
- Nasopharyngeal Carcinoma
Interventions
- DIAGNOSTIC_TEST
-
Nasopharngeal brush
1. Baseline nasopharngeal brush before treatment 2. Post-treatment reassessment of residual NPC
Sponsors & Collaborators
-
The University of Hong Kong
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-01-31
- Primary Completion
- 2018-12-31
- Completion
- 2018-12-31
More Related Trials
-
Comparison of Multi-omics Models for Early Nasopharyngeal Carcinoma Screening: CfDNA Methylation, EBV DNA, and Serological Double-antibodies Detection
NCT06763289 ·Status: RECRUITING
-
Prospective Study for Molecular Biomarkers of Normal Nasopharyngeal Tissue
NCT03048305 ·Status: UNKNOWN
-
To Establish a Molecular Typing System for Early Diagnosis of Lung Cancer
NCT05432128 ·Status: RECRUITING
-
Early Lung Cancer Detection in Patients With Sputum Cytology and Autofluorescence Bronchoscopy in People at High Risk of Lung Cancer
NCT00563420 ·Status: COMPLETED ·Phase: NA
-
Prognostic Value of TIL in Nasopharyngeal Carcinoma
NCT06763640 ·Status: ENROLLING_BY_INVITATION
-
A Multi-center Prospective Observational Biomarker Study on EGFRm+ Non-small Cell Lung Cancer Patients With Leptomeningeal Metastasis
NCT02803619 ·Status: UNKNOWN
-
Predictive Biomarkers for Pneumonitis After Chemoradiotherapy and Immunotherapy in Patients With Non-small Cell Lung Cancer
NCT04913311 ·Status: RECRUITING
-
Detection of EGFR Mutation in Malignant Pleural Effusion of Lung Cancer Patients and Cancer Cell Lines Establishment
NCT00752076 ·Status: UNKNOWN ·Phase: NA
-
Tertiary Lymphoid Structures in Nasopharyngeal Carcinoma
NCT06770699 ·Status: ACTIVE_NOT_RECRUITING
-
Detection and Biopsy Guidance of Nasopharyngeal Carcinoma Based on Artificial Intelligence and Endoscopic Images
NCT05202626 ·Status: RECRUITING
-
Radiogenomics in Aerodigestive Tract Cancers
NCT04314349 ·Status: COMPLETED
-
Prospective Evaluation of Immunological, Molecular-genetic, Image-based and Microbial Analyzes to Characterize Tumor Response and Control in Patients With Inoperable Stage III NSCLC Treated With Chemoradiotherapy Followed by Consolidation Therapy With Durvalumab
NCT05027165 ·Status: UNKNOWN
-
Development and Validation of a Deep Learning System for Nasopharyngeal Carcinoma Using Endoscopic Images
NCT05627310 ·Status: UNKNOWN
-
Prospective Study for Prognostic Biomarkers of Nasopharyngeal Carcinoma
NCT03025854 ·Status: UNKNOWN
-
Validation of Soluble Programmed Death-1 in Predicting Progression of Nodular-bronchiectatic Form of Nontuberculous Mycobacterial Lung Disease: a Multi-Country Research
NCT05678166 ·Status: UNKNOWN
-
Identification and Validation of Blood-Based Biomarkers for Early Detection of Asymptomatic Lung Cancer in High-Risk Heavy Smokers
NCT06816121 ·Status: RECRUITING
-
Gene Mutations in Non-Small Cell Lung Cancer Cells
NCT00977509 ·Status: UNKNOWN
-
Therapeutic ResistAnce and Clonal Evolution Assessed With Liquid Biopsy of NSCLC Patients in China
NCT03059641 ·Status: COMPLETED
-
Effect of Nurse-Led Individualized Follow-Up Intervention on Patients With Nasopharyngeal Carcinoma
NCT06572293 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Evaluation of Clinical Significance and Feasibility of CT Guided Biopsy of Double Site Lesions:A Preliminary Lung Centered Study
NCT04960631 ·Status: COMPLETED
-
Proton Therapy to Reduce Acute Normal Tissue Toxicity in Locally Advanced Non-small-cell Lung Cancer
NCT02731001 ·Status: RECRUITING ·Phase: NA
-
Efficacy and Safety of Chemoimmunotherapy and Carbon Ion Radiotherapy in Unresectable Locally Advanced Non-small Cell Lung Cancer
NCT07035860 ·Status: NOT_YET_RECRUITING
-
Studying Tumor Tissue Samples From Patients With Early-Stage Non-Small Cell Lung Cancer
NCT01517971 ·Status: COMPLETED
-
Feasibility of Targeted Bronchial Washing for Molecular Testing by Next Generation Sequencing in Early-stage Lung Cancer
NCT06301295 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Molecular Profiling and Dynamic Changes of ctDNA in Unresectable Locally Advanced NSCLC
NCT05641870 ·Status: UNKNOWN