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coMparison Between invAsive and Non-invasive assessmenT on Blood Pressure and Cardiac Function in HealthY Participants

NCT03372616 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2017-12-13

No results posted yet for this study

Summary

This is a cross-sectional cohort study which aims to compare the invasive and non-invasive assessments on aortic blood pressure and cardiac funtion in subjects without history of cardio-vascular disease. Left ventricular (LV) filling pressure, LV volume, and aortic blood pressure will be measured invasively. Non-invasive assessment includes echocardiography,aortic, and carotid blood pressure measurement.

Conditions

  • Healthy Volunteer

Interventions

DIAGNOSTIC_TEST

Invasive left ventricular diastolic function assessment

Left ventricular (LV) polyethylene catheter was inserted into left ventricular to directly measure LV filling pressure.

DIAGNOSTIC_TEST

Invasive aortic blood pressure measurement

Aortic blood pressure will be measured with polyethylene catheter in aortic root.

DIAGNOSTIC_TEST

Non-Invasive left ventricular diastolic function assessment

Echocardiography will be performed in all participants to assess left ventricular diastolic function non-invasively.

DIAGNOSTIC_TEST

Non-Invasive aortic blood pressure measurement

Three devices (Sphygmocor \[AtCor Medical, Australia\], PulsePen \[DiaTecne SRL, Italy\], and Mobil-O-Graph \[IEM, Germany\] ) will be used to assess aortic blood pressure non-invasively when participants are undergoing invasive aortic blood pressure measurement.

Sponsors & Collaborators

  • Shanghai 10th People's Hospital

    lead OTHER

Principal Investigators

  • Yawei Xu, M.D., Ph.D. · Shanghai 10th People's Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-01-31
Primary Completion
2018-03-31
Completion
2018-06-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03372616 on ClinicalTrials.gov