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The Platelet-Rich Plasma in the Therapy of Temporomandibular Disorders

NCT03371888 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 58

Last updated 2019-01-04

No results posted yet for this study

Summary

The Platelet-Rich Plasma intramuscular injections into the masseter and temporalis muscle were performed to reduce painful temporomandibular disorder symptoms,such as myalgia, myofascial pain and myofascial pain with referrals. Patients(n=120) were randomly divided into two groups: experimental(n=60) and control group(n=60). In controls injections with 0,9% NaCl were performed. Pain intensity was measured with NPRS (numeriic pain rating scale, 0= no pain, 11= the worst pain that one can imagine) before(0 day), during(10 day) and after(20 day) the therapy with PRP injections.

Conditions

  • PRP
  • Temporomandibular Disorder
  • Myalgia
  • Bruxism

Interventions

BIOLOGICAL

Platelet-Rich Plasma intramuscular injections

A platelet-rich plasma intramuscular injections into the trigger points of painful muscles were performed.

BIOLOGICAL

Placebo Comparator: 0,9% NaCl intramuscular injections

A 0,9% NaCl intramuscular injections into the trigger points of painful muscles were performed.

Sponsors & Collaborators

  • Medical University of Silesia

    lead OTHER

Principal Investigators

  • Aleksandra Nitecka-Buchta, DMD · Medical University of Silesia

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
23 Years
Max Age
42 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-12-07
Primary Completion
2018-12-15
Completion
2019-01-01

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03371888 on ClinicalTrials.gov