Vaccine Therapy in Treating Patients With Recurrent Glioblastoma
NCT03360708 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2023-06-28
Summary
This pilot early phase I trial studies the side effects of vaccine therapy in treating patients with glioblastoma that has come back. Vaccines made from a person's white blood cells mixed with tumor proteins from another person's glioblastoma tumors may help the body build an effective immune response to kill tumor cells. Giving vaccine therapy may work better in treating patients with glioblastoma.
Conditions
- Giant Cell Glioblastoma
- Recurrent Glioblastoma
- Recurrent Gliosarcoma
Interventions
- OTHER
-
Laboratory Biomarker Analysis
Correlative studies
- BIOLOGICAL
-
Malignant Glioma Tumor Lysate-Pulsed Autologous Dendritic Cell Vaccine
Given ID
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Ian Parney · Mayo Clinic
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-11-27
- Primary Completion
- 2021-06-02
- Completion
- 2021-06-02
- FDA Drug
- Yes
Countries
- United States
Study Locations
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