Correlation of Eicosanoid and Proresolving Lipid Mediator Temporal Profiles and Resolution of Pain After Thoracic Surgery
NCT03360175 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 40
Last updated 2017-12-04
Summary
The aim of the current pilot study is to investigate whether perioperative dysregulated systemic lipid mediator pathways (more specifically increased pro-inflammatory and decreased anti-inflammatory pathways) are associated with slower resolution of pain after surgery and increased risk for development of persistent postsurgical pain (PPSP). In addition, we will look for correlations between the pro-resolving lipid mediator profile and Quality of Recovery (QoR-15), duration of hospital stay, and frequency of complications, e.g. wound infections.
Conditions
- Pain, Postoperative
Interventions
- OTHER
-
No intervention - observational study
No intervention - observational study
Sponsors & Collaborators
-
Brigham and Women's Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-12-11
- Primary Completion
- 2019-07-01
- Completion
- 2019-12-01
More Related Trials
-
Cytokine Alterations and Chronic Post-Surgical Pain
NCT06418295 ·Status: NOT_YET_RECRUITING
-
Chronic Pain After Operation for Breast Cancer
NCT00739544 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Speeding Recovery From Pain and Opioid Use
NCT03388814 ·Status: WITHDRAWN ·Phase: EARLY_PHASE1
-
PREventing Pain After Surgery
NCT05306665 ·Status: RECRUITING ·Phase: NA
-
Prediction and Characterization of Acute and Chronic Postoperative Pain
NCT01308385 ·Status: COMPLETED
-
Pain and Magnesium
NCT03063931 ·Status: UNKNOWN ·Phase: PHASE2
-
Sex Hormones, Postoperative Pain and Opioid Use
NCT06023225 ·Status: RECRUITING
-
Multimodal Analgesia Versus Routine Care Pain Management
NCT01861743 ·Status: TERMINATED ·Phase: NA
-
Intravenous Acetaminophen/Ibuprofen Fixed-dose Combination on Postoperative Opioid Consumption
NCT05366777 ·Status: COMPLETED ·Phase: NA
-
Neuraxial and Neurolytic Analgesia for Intractable Pain
NCT00167726 ·Status: COMPLETED
-
Prospectively Assessing Pain After Breast Surgery
NCT05210400 ·Status: UNKNOWN
-
Phenomics and Genomics of Clinically Relevant Chronic Postsurgical Pain
NCT04798573 ·Status: ACTIVE_NOT_RECRUITING
-
Evaluation of Pain Trajectories After Surgery and Their Potential Relationship With Chronicity at 3 Months
NCT05326737 ·Status: UNKNOWN
-
Predicting Chronic Pain Following Breast Surgery
NCT04967352 ·Status: UNKNOWN
-
Postoperative Opioid Use and Pain Scores in Patients Undergoing Transforaminal Lumbar Interbody Fusion
NCT02061774 ·Status: TERMINATED ·Phase: PHASE4
-
Evaluation of Open-Label Conditioned Placebo Analgesia for Postoperative Opioid Reduction Following Spinal Fusion
NCT04574388 ·Status: COMPLETED ·Phase: NA
-
Post-Operative Pain Management With NSAIDS
NCT01971372 ·Status: COMPLETED
-
Non-Pharmacological Interventions on Patient Experience and Healthcare Utilization in Adult Cardiac Surgery Patients
NCT04051021 ·Status: COMPLETED ·Phase: NA
-
A Study on Analgesia and Related Outcomes for Patients With Tabacco Smoking
NCT02266212 ·Status: COMPLETED ·Phase: NA
-
Perioperative Systemic Acetaminophen to Improve Postoperative Quality of Recovery After Ambulatory Breast Surgery
NCT01852955 ·Status: COMPLETED ·Phase: NA
-
Characterization of Post-operative Pain Trajectories Over Seven Days and Links With Chronicity
NCT02599233 ·Status: COMPLETED
-
Opioid Free Anesthesia: What About Patient Comfort?
NCT02882035 ·Status: COMPLETED ·Phase: PHASE4
-
Development of a Personalised Care Plan Designed to Reduce Chronic Post-Operative Pain Following Breast Surgery
NCT02170415 ·Status: UNKNOWN ·Phase: NA
-
Post-Operative Pain Management Following Spine Surgery
NCT03076710 ·Status: WITHDRAWN
-
Reducing Chronic Pain After Lung Surgery: A Trial of Limiting NSAIDs During Recovery
NCT07108582 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3