MedTrace Logo

Topical Versus Oral Metronidazole Following Excisional Haemorrhoidectomy

NCT03343509 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2020-11-03

No results posted yet for this study

Summary

This study aims to determine if topical metronidazole reduces pain more than oral metronidazole following excisional haemorrhoidectomy. The trial will be a multi-centered, patient and investigator blinded superiority trial with two parallel groups and a primary outcome of pain scores during 14 days after surgery.

Group A will receive oral metronidazole and placebo cream. Group B will receive placebo tablets and topical metronidazole cream.

Conditions

Interventions

DRUG

Metronidazole Oral

Oral Metronidazole

DRUG

Metronidazole Ointment

Metronidazole Ointment

DRUG

Placebo Oral Tablet

Placebo Tablet

DRUG

Placebo Ointment

Placebo Ointment

Sponsors & Collaborators

  • University of Auckland, New Zealand

    lead OTHER

Principal Investigators

  • Andrew G Hill, MBChB · The University of Auckland

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-03-11
Primary Completion
2020-02-01
Completion
2020-02-01

Countries

  • New Zealand

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03343509 on ClinicalTrials.gov