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Comparison of Dexmedetomidine and Midazolam for Prevention of Emergence Delirium in Children

NCT03337672 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2019-01-09

No results posted yet for this study

Summary

Emergence delirium is a common complication in children after anesthesia. The incidence of emergence delirium is reported upto 50%. Prevention of emergence delirium in children is important not only for the patient safety but also for the satisfaction of the parents. Midazolam is the most commonly used medications for prevention of emergence delirium. However, it might lead to delayed awakening from anesthesia and respiratory depression. In this study, the investigators will evaluate whether dexmedetomidine can be effectively and safely administered for prevention of emergence delirium in children compared to midazolam.

Conditions

  • Tonsillitis

Interventions

DRUG

Dexmedetomidine

Intravenous dexmedetomidine 0.3mcg/kg is slowly infused at 5 minutes before the end of surgery

DRUG

Midazolam

Intravenous dexmedetomidine 0.03mg/kg is slowly infused at 5 minutes before the end of surgery

Sponsors & Collaborators

  • Eunah Cho, MD

    lead OTHER

Principal Investigators

  • Eunah Cho, M.D. · Kangbuk Samsung Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
24 Months
Max Age
12 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-12-05
Primary Completion
2018-12-17
Completion
2018-12-17

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03337672 on ClinicalTrials.gov