Trial Outcomes & Findings for Using Virtual Reality (VR) Models for Preoperative Planning (NCT NCT03334344)

NCT ID: NCT03334344

Last Updated: 2024-08-29

Results Overview

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

92 participants

Primary outcome timeframe

During procedure

Results posted on

2024-08-29

Participant Flow

Participant milestones

Participant milestones
Measure
Intervention Arm
Subjects whose surgeon will be viewing VR models in connection with the in addition to the source CT/MR image Ceevra Reveal: VR models generated using Ceevra Reveal are viewed by surgeons in connection with the case in addition to source CT/MR image.
Control Arm
Subjects whose surgeon will only be viewing CT/MR images in connection with the case
Overall Study
STARTED
44
48
Overall Study
COMPLETED
44
48
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Using Virtual Reality (VR) Models for Preoperative Planning

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Intervention Arm
n=44 Participants
Subjects whose surgeon will be viewing VR models in connection with the in addition to the source CT/MR image Ceevra Reveal: VR models generated using Ceevra Reveal are viewed by surgeons in connection with the case in addition to source CT/MR image.
Control Arm
n=48 Participants
Subjects whose surgeon will only be viewing CT/MR images in connection with the case
Total
n=92 Participants
Total of all reporting groups
Age, Continuous
64.6 years
STANDARD_DEVIATION 9.7 • n=99 Participants
57.6 years
STANDARD_DEVIATION 9.7 • n=107 Participants
60.9 years
STANDARD_DEVIATION 11.6 • n=206 Participants
Sex: Female, Male
Female
15 Participants
n=99 Participants
19 Participants
n=107 Participants
34 Participants
n=206 Participants
Sex: Female, Male
Male
29 Participants
n=99 Participants
29 Participants
n=107 Participants
58 Participants
n=206 Participants
Race/Ethnicity, Customized
White
36 Participants
n=99 Participants
38 Participants
n=107 Participants
74 Participants
n=206 Participants
Race/Ethnicity, Customized
Non-White
8 Participants
n=99 Participants
10 Participants
n=107 Participants
18 Participants
n=206 Participants
Region of Enrollment
United States
44 participants
n=99 Participants
48 participants
n=107 Participants
92 participants
n=206 Participants

PRIMARY outcome

Timeframe: During procedure

Outcome measures

Outcome measures
Measure
Intervention Arm
n=44 Participants
Subjects whose surgeon will be viewing VR models in connection with the in addition to the source CT/MR image Ceevra Reveal: VR models generated using Ceevra Reveal are viewed by surgeons in connection with the case in addition to source CT/MR image.
Control Arm
n=48 Participants
Subjects whose surgeon will only be viewing CT/MR images in connection with the case
Total Operative Time
163 minutes
Interval 146.5 to 200.0
173.5 minutes
Interval 148.0 to 199.0

SECONDARY outcome

Timeframe: Measured at end of procedure

Outcome measures

Outcome measures
Measure
Intervention Arm
n=44 Participants
Subjects whose surgeon will be viewing VR models in connection with the in addition to the source CT/MR image Ceevra Reveal: VR models generated using Ceevra Reveal are viewed by surgeons in connection with the case in addition to source CT/MR image.
Control Arm
n=48 Participants
Subjects whose surgeon will only be viewing CT/MR images in connection with the case
Blood Loss
124.5 cc
Standard Deviation 90.5
145.7 cc
Standard Deviation 140.4

SECONDARY outcome

Timeframe: Measured at end of procedure

Outcome measures

Outcome measures
Measure
Intervention Arm
n=44 Participants
Subjects whose surgeon will be viewing VR models in connection with the in addition to the source CT/MR image Ceevra Reveal: VR models generated using Ceevra Reveal are viewed by surgeons in connection with the case in addition to source CT/MR image.
Control Arm
n=48 Participants
Subjects whose surgeon will only be viewing CT/MR images in connection with the case
Clamp Time
18 minutes
Interval 12.0 to 22.0
18 minutes
Interval 15.0 to 24.0

SECONDARY outcome

Timeframe: During procedure

Outcome measures

Outcome measures
Measure
Intervention Arm
n=44 Participants
Subjects whose surgeon will be viewing VR models in connection with the in addition to the source CT/MR image Ceevra Reveal: VR models generated using Ceevra Reveal are viewed by surgeons in connection with the case in addition to source CT/MR image.
Control Arm
n=48 Participants
Subjects whose surgeon will only be viewing CT/MR images in connection with the case
Number of Patients With Conversion to Open Surgery
0 Participants
0 Participants

SECONDARY outcome

Timeframe: During procedure

Outcome measures

Outcome measures
Measure
Intervention Arm
n=44 Participants
Subjects whose surgeon will be viewing VR models in connection with the in addition to the source CT/MR image Ceevra Reveal: VR models generated using Ceevra Reveal are viewed by surgeons in connection with the case in addition to source CT/MR image.
Control Arm
n=48 Participants
Subjects whose surgeon will only be viewing CT/MR images in connection with the case
Number of Patients With Conversion to Radical Nephrectomy
3 Participants
3 Participants

SECONDARY outcome

Timeframe: During procedure

Outcome measures

Outcome measures
Measure
Intervention Arm
n=44 Participants
Subjects whose surgeon will be viewing VR models in connection with the in addition to the source CT/MR image Ceevra Reveal: VR models generated using Ceevra Reveal are viewed by surgeons in connection with the case in addition to source CT/MR image.
Control Arm
n=48 Participants
Subjects whose surgeon will only be viewing CT/MR images in connection with the case
Number of Patients With an Intraoperative Complication
1 Participants
0 Participants

SECONDARY outcome

Timeframe: Measured at time of patient discharge, up to 10 days

Outcome measures

Outcome measures
Measure
Intervention Arm
n=44 Participants
Subjects whose surgeon will be viewing VR models in connection with the in addition to the source CT/MR image Ceevra Reveal: VR models generated using Ceevra Reveal are viewed by surgeons in connection with the case in addition to source CT/MR image.
Control Arm
n=48 Participants
Subjects whose surgeon will only be viewing CT/MR images in connection with the case
Patient Hospital Stay
1.5 Days
Standard Deviation 0.8
1.64 Days
Standard Deviation 0.9

SECONDARY outcome

Timeframe: Measured 1-2 weeks after discharge

Incomplete removal of tumor as defined by the surgical pathology

Outcome measures

Outcome measures
Measure
Intervention Arm
n=44 Participants
Subjects whose surgeon will be viewing VR models in connection with the in addition to the source CT/MR image Ceevra Reveal: VR models generated using Ceevra Reveal are viewed by surgeons in connection with the case in addition to source CT/MR image.
Control Arm
n=48 Participants
Subjects whose surgeon will only be viewing CT/MR images in connection with the case
Number of Patients With a Positive Surgical Margin
0 Participants
0 Participants

SECONDARY outcome

Timeframe: Measured up to 6 months after discharge

Outcome measures

Outcome measures
Measure
Intervention Arm
n=44 Participants
Subjects whose surgeon will be viewing VR models in connection with the in addition to the source CT/MR image Ceevra Reveal: VR models generated using Ceevra Reveal are viewed by surgeons in connection with the case in addition to source CT/MR image.
Control Arm
n=48 Participants
Subjects whose surgeon will only be viewing CT/MR images in connection with the case
Post-Op Complication
4 Participants
2 Participants

SECONDARY outcome

Timeframe: Measured up to 6 months after discharge

Outcome measures

Outcome measures
Measure
Intervention Arm
n=44 Participants
Subjects whose surgeon will be viewing VR models in connection with the in addition to the source CT/MR image Ceevra Reveal: VR models generated using Ceevra Reveal are viewed by surgeons in connection with the case in addition to source CT/MR image.
Control Arm
n=48 Participants
Subjects whose surgeon will only be viewing CT/MR images in connection with the case
Readmission
4 Participants
2 Participants

Adverse Events

Intervention Arm

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Control Arm

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Russ Yoshinaka

Ceevra

Phone: 415-926-9434

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place