Real World Outcomes of Intravitreal Anti-vascular Endothelial Growth Factors for Neovascular Age Related Macular Degeneration in Taiwan
NCT03324542 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 63
Last updated 2018-07-20
Summary
Purpose To report the long-term efficacy of patients with neovascular age-related macular degeneration (nAMD) treated with anti-vascular endothelial growth factor (VEGF) in Changhua Christian Hospital in Taiwan.
Method Retrospective case series of patients with nAMD that were treated with intravitreal injection of anti-VEGF and had a minimum follow up of 48 months. Every patient was initially treated with 3 loading doses of either bevacizumab or ranibizumab, followed by a loose treat and extend regimen. Eyes were divided into 2 groups according to whether aflibercept was later used as a rescue therapy (group 2) or not (group 1). Patients underwent best-corrected visual acuity (BCVA) testing, optical coherence tomography, and ophthalmic examination at baseline and all the scheduled follow-up visits.
Conditions
Interventions
- DRUG
-
Aflibercept [Eylea]
Anti-vascular endothelial growth factor (VEGF)
Sponsors & Collaborators
-
Changhua Christian Hospital
lead OTHER
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-04-03
- Primary Completion
- 2017-10-13
- Completion
- 2017-10-15
Countries
- Taiwan
Study Locations
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