Quantitative Polymerase Chain Reaction for Improved Detection of Pneumococci in CAP "CAPTAIN"
NCT03315403 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 922
Last updated 2022-04-08
Summary
The purpose of this study is to evaluate the added diagnostic value of a quantitative polymerase chain reaction targeting the lytA gene in detecting pneumococci in patients with community-acquired pneumonia.
Conditions
- Pneumonia, Pneumococcal
- Community-acquired Pneumonia
Interventions
- DIAGNOSTIC_TEST
-
LytA targeted quantitative polymerase chain reaction (qPCR)
LytA qPCR and cultures will be performed on samples of the upper respiratory tract (nasopahrynx, oropharynx, saliva, sputum if available)
Sponsors & Collaborators
-
Medical Center Alkmaar
lead OTHER
Principal Investigators
-
Wim Boersma, MD. PhD. · Noordwest Ziekenhuisgroep
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-04-05
- Primary Completion
- 2020-03-12
- Completion
- 2020-03-12
Countries
- Netherlands
Study Locations
More Related Trials
-
Impact of Comprehensive Molecular Tests on Antimicrobial Stewardship in Community-acquired Pneumonia
NCT04158492 ·Status: TERMINATED ·Phase: NA
-
A Phase III Study of Faropenem in the Treatment of Adult Community-acquired Bacterial Pneumonia
NCT01937832 ·Status: UNKNOWN ·Phase: PHASE3
-
Improved Use of Antibiotic Guidelines in Hospital Environment
NCT00512772 ·Status: COMPLETED
-
Costs, Health Status and Outcomes of CAP (Community-Acquired Pneumonia)
NCT00812084 ·Status: COMPLETED
-
Telithromycin, Treating Adult Outpatients With Mild to Moderate Community-acquired Pneumonia (CAP) in High Bacterial Resistance Areas
NCT00538018 ·Status: COMPLETED ·Phase: PHASE4
-
Carriage of Streptococcus Pneumoniae in Infants With Acute Otitis Media and in Infants Attending Day-care Centers
NCT02888457 ·Status: COMPLETED ·Phase: NA
-
Pathogen Detection and Community Acquired Pneumonia
NCT02880384 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Respiratory Specimens for Bacterial and Viral Pathogens by Real-Time PCR
NCT00275691 ·Status: COMPLETED
-
Point-of-Care Multiplex for Adult Patients With Severe Community-acquired Pneumonia
NCT04835818 ·Status: UNKNOWN ·Phase: NA
-
Community-Acquired Pneumonia - Study on the Initial Treatment With Antibiotics of Lower Respiratory Tract Infections
NCT01660204 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of SR1375 in Adult Patients With CAP
NCT06577558 ·Status: RECRUITING ·Phase: PHASE2
-
Urinary Antigen Test for Stretococcus Pneumoniae Serotype Prevalence in Community Acquired Pneumonia
NCT05374018 ·Status: ACTIVE_NOT_RECRUITING
-
A Phase II Study of Faropenem in the Treatment of Adult Community-acquired Bacterial Pneumonia
NCT01886053 ·Status: COMPLETED ·Phase: PHASE2
-
Community-Acquired Pneumonia Diagnosis Through Integrating Novel Microbiological Techniques.
NCT06259110 ·Status: NOT_YET_RECRUITING
-
A Global Active Surveillance for Community Acquired Pneumonia
NCT00929721 ·Status: COMPLETED ·Phase: NA
-
Impact on the Use of Antibiotics of a Multimodal Algorithm for the Diagnosis and Management of Acute Community-acquired Pneumonia in the Emergency Room
NCT05657275 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of Colistimethate Sodium Injection Vial to Treat Hospital-acquired Pneumonia in Adults
NCT01940731 ·Status: UNKNOWN ·Phase: PHASE2
-
Rapid Analysis of Infections by Spectrometry of Exhaled Breath
NCT03299608 ·Status: RECRUITING
-
Description of Pneumococcal Pneumonia
NCT03322670 ·Status: COMPLETED
-
Pneumococcal Nasopharyngeal Colonization as Predictor of Community-Acquired Pneumonia (CAP) in Adults With Chronic Diseases.
NCT04944719 ·Status: UNKNOWN
-
Urine Pneumococcal Antigen Project
NCT07181200 ·Status: NOT_YET_RECRUITING
-
Determination of the Utility of Pfizer's Pneumococcal Urine Antigen Test in Children 5 Years of Age or Younger With Community Acquired Pneumonia in Guatemala
NCT03696303 ·Status: COMPLETED
-
Etiology of Community Acquired Pneumonia
NCT00471757 ·Status: COMPLETED
-
Validity of Biological Material Sampling in Patients With Hospital-acquired Pneumonia
NCT03039998 ·Status: COMPLETED
-
Impact of Legionella Urine Antigen Testing (LUAT) on the Local Epidemiology and Diagnosis of Legionella Pneumonia
NCT03200275 ·Status: COMPLETED