MedTrace Logo

Initial Hemopurification Strategy for Acute Paraquat Poisoning in Adults

NCT03314909 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 360

Last updated 2018-04-17

No results posted yet for this study

Summary

HeSAPP is a single-center, non-blinded, parallel-group randomized controlled trial studying the hemopurification strategy for acute paraquat(PQ) poisoned patients. The intervention to be investigated include hemodialysis (HD), hemoperfusion (HP), combined hemoperfusion-hemodialysis concurrent therapy (HP-HD) and conservative therapy. The object of the present trial is to investigate whether hemopurification therapy can reduce mortality compared with conservative therapy.

Conditions

  • Poisoning

Interventions

PROCEDURE

Hemodialysis

Participants in this group will be catheterize in the internal jugular vein and connect to a hemodialysis machine.

PROCEDURE

Hemoperfusion

Participants in this group will be catheterize in the internal jugular vein and connect to a hemoperfusion machine.

PROCEDURE

HP-HD

Participants in this group will be catheterize in the internal jugular vein and connect to a hemoperfusion machine and then a hemodialysis machine for one course.

Sponsors & Collaborators

  • The First Affiliated Hospital of Zhengzhou University

    collaborator OTHER

  • National Natural Science Foundation of China

    collaborator OTHER_GOV

  • Peking Union Medical College Hospital

    lead OTHER

Principal Investigators

  • Yi Li, M.D. · Peking Union Medical College Hospital

  • Yanxia Gao · The First Affiliated Hospital of Zhengzhou University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-10-01
Primary Completion
2021-12-31
Completion
2022-02-28

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03314909 on ClinicalTrials.gov