Immunological Profile of Solid Tumors Sample
NCT03311100 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1040
Last updated 2018-01-30
Summary
It has become clear in the recent year that the nature of the immune cells infiltrate within a tumor was essential in the control of the tumor growth. This so-called immune contexture does vary between cancer types and in response to treatments. In this context, this trial is a non-interventional, mono-centric in patients with solid tumors. Samples in paraffin-embedded material block of biopsies or surgical pieces (either primitive tumor or metastases) will be analysed. For each sample, clinically relevant data associated with treated cancer and needed for characterization of tumor microenvironment will be documented.
This trial is, through accessing to well documented selected archival tumor materials, to validate selected biomarker for early phase trial.
Conditions
- Solid Cancer
Interventions
- OTHER
-
immunohistochemistry assay
biomarkers expression
Sponsors & Collaborators
-
Innate Pharma
collaborator INDUSTRY -
Assistance Publique Hopitaux De Marseille
lead OTHER
Principal Investigators
-
ARNAUD Jean-Olivier, Director · Assistance Publique Hôpitaux de Marseille
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-04-06
- Primary Completion
- 2019-04-06
- Completion
- 2020-04-06
Countries
- France
Study Locations
More Related Trials
-
Treatment of Metastatic Melanoma With Autologous Melan-A/MART-1 Specific CTL Clones
NCT00720031 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of Immunotherapy With TIL (Tumor Infiltrating Lymphocytes) in Combination With Intra-tumoral Injections of Interferon Gamma-adenovirus (Ad-IFNg) in Patients With Stage IIIc or Stage IV Metastatic Melanoma (AJCC)(Protocol TIL-Ad-INFg)
NCT01082887 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Exploratory Study of IMM01 for Injection in the Treatment of Refractory or Recurrent Hematologic Malignancy
NCT05860075 ·Status: TERMINATED ·Phase: PHASE1
-
Immunotherapy in MSI/dMMR Tumors in Perioperative Setting.
NCT04795661 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Dose-escalation Study of IMC-001 in Subject With Metastatic or Locally-advanced Solid Tumors
NCT03644056 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of IMC-002 in Subjects With Metastatic or Locally Advanced Solid Tumors and Relapsed or Refractory Lymphomas
NCT04306224 ·Status: COMPLETED ·Phase: PHASE1
-
Oral Pooled Fecal Microbiotherapy (MaaT033) Concomitant to Cemiplimab Versus Best Investigator's Choice in Patients With Resistance to Treatment Due to Antibiotics Uptake With Advanced Non-small Cell Lung Cancer
NCT07001618 ·Status: RECRUITING ·Phase: PHASE2
-
Radiotherapy As an Immunological Booster in Patients with Metastatic Melanoma or Renal Cell Carcinoma Treated with High-dose Interleukin-2
NCT01884961 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of GC101 TIL in Advanced Melanoma
NCT06703398 ·Status: RECRUITING ·Phase: PHASE2
-
Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-MT) for Patients With Melanoma.
NCT00688090 ·Status: COMPLETED ·Phase: PHASE1
-
A Randomized, Double-blind, Placebo-controlled, Single and Multiple Dose Escalation Phase I Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of IMC-003 for Injection in Healthy Postmenopausal Women
NCT07118085 ·Status: RECRUITING ·Phase: PHASE1
-
Phase 1 Study of IM156 in Patients With Advanced Solid Tumor and Lymphoma
NCT03272256 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of IMM-6-415 in RAS/RAF Mutant Solid Tumors
NCT06208124 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Laboratory-Treated T Cells and Ipilimumab in Treating Patients With Metastatic Melanoma
NCT00871481 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Melanoma
NCT01993719 ·Status: COMPLETED ·Phase: PHASE2
-
The IIT Study of Evaluation of P-IL-2 Single Agent and With Anti-PD-1
NCT05829057 ·Status: RECRUITING ·Phase: PHASE1
-
A Phase I Study of GC101 TIL in Advanced Solid Tumors
NCT05417750 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Ipilimumab in the Immune System
NCT01715077 ·Status: COMPLETED ·Phase: NA
-
Prospective Cohort With Clinic-biologic Database of Patients Treated by Immunotherapy
NCT05223608 ·Status: RECRUITING ·Phase: NA
-
Safety, Immune and Tumor Response to a Multi-component Immune Based Therapy (MKC1106-MT) for Patients With Melanoma
NCT01026051 ·Status: TERMINATED ·Phase: PHASE2
-
IMCgp100 in Advanced Unresectable Melanoma
NCT01209676 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Ex-vivo Evaluation of the Reactivity of the Immune Infiltrate of Cancers to Treatments With Monoclonal Antibodies Targeting the Immunomodulatory Pathways
NCT04349293 ·Status: UNKNOWN ·Phase: NA
-
Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors
NCT03645928 ·Status: TERMINATED ·Phase: PHASE2
-
Intratumoral CAN1012(Selective TLR7 Agonist) in Subjects With Solid Tumors
NCT04987112 ·Status: RECRUITING ·Phase: PHASE1
-
A Phase 1 Study of INCMGA00012 in Patients With Advanced Solid Tumors
NCT03059823 ·Status: COMPLETED ·Phase: PHASE1