Association Between Plasma Melatonin and No-reflow
NCT03306303 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1700
Last updated 2017-10-11
Summary
ST-segment elevation myocardial infarction (STEMI) is an acute manifestation of coronary heart disease, remaining a frequent cause of death. A better understanding of risk factors and pathogenic mechanisms underlying STEMI may help improve the prognosis and life quality of these patients. Melatonin is the chief indoleamine produced by the pineal gland, and a well-known antioxidant and free radical scavenger. Basic studies have showed that melatonin is associated with myocardial infarction and heart failure. However, no study has evaluated whether melatonin is associated with adverse clinical outcomes in STEMI patients.
Conditions
- ST-segment Elevation Myocardial Infarction
Sponsors & Collaborators
-
Chinese PLA General Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-01-01
- Primary Completion
- 2017-10-01
- Completion
- 2017-10-01
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