Trial Outcomes & Findings for Rapid MRI for Acute Pediatric Head Trauma (NCT NCT03291964)

NCT ID: NCT03291964

Last Updated: 2023-01-26

Results Overview

Sensitivity of Rapid MRI for detection of a clinically important intracranial injury: Percentage of MRIs identifying clinically important intracranial injury. Sensitivity was calculated as the number of true positives divided by "true positive plus false negative". True positive was defined based on meeting clinical criteria for a clinically important TBI and if the imaging found the injury.

Recruitment status

COMPLETED

Target enrollment

76 participants

Primary outcome timeframe

within 6 hours from the initial head CT

Results posted on

2023-01-26

Participant Flow

Participant milestones

Participant milestones
Measure
Quick Brain
Pediatric head trauma patients
Overall Study
STARTED
73
Overall Study
COMPLETED
73
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Rapid MRI for Acute Pediatric Head Trauma

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Quick Brain
n=73 Participants
Pediatric head trauma patients
Age, Categorical
<=18 years
73 Participants
n=99 Participants
Age, Categorical
Between 18 and 65 years
0 Participants
n=99 Participants
Age, Categorical
>=65 years
0 Participants
n=99 Participants
Age, Continuous
4.0 years
n=99 Participants
Sex: Female, Male
Female
38 Participants
n=99 Participants
Sex: Female, Male
Male
35 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
0 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
0 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
73 Participants
n=99 Participants
Region of Enrollment
United States
73 participants
n=99 Participants

PRIMARY outcome

Timeframe: within 6 hours from the initial head CT

Sensitivity of Rapid MRI for detection of a clinically important intracranial injury: Percentage of MRIs identifying clinically important intracranial injury. Sensitivity was calculated as the number of true positives divided by "true positive plus false negative". True positive was defined based on meeting clinical criteria for a clinically important TBI and if the imaging found the injury.

Outcome measures

Outcome measures
Measure
Quick Brain
n=73 Participants
Pediatric head trauma patients
Sensitivity: Percentage of MRIs Correctly Identifying Clinically Important Intracranial Injury (True Positives)
70 Percentage of MRIs correctly identifying

SECONDARY outcome

Timeframe: During initial ER stay within 3 hours from time of entry to the ER

minutes

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: During initial ER stay within 3 hours from time of entry to the ER

Number of patients requiring medication to obtain imaging

Outcome measures

Outcome data not reported

Adverse Events

Quick Brain

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

David Sheridan Assistant Prof

Oregon Health and Science university

Phone: 5034941691

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place