Pilot of Lifestyle and Asthma Intervention

Summary

This is to pilot test a weight loss intervention in obese patients with poorly controlled asthma.

Obesity is a risk factor for the development of asthma (approximately 250,000 cases per year of asthma in the U.S. are related to obesity).

Investigators' ultimate purpose is to test the hypothesis that weight loss through an intensive life style intervention will improve asthma control. But investigators first need to establish whether the weight loss intervention is effective in patients with asthma.

Objectives

1. The primary objective of this study is to determine the effectiveness of an internet-based weight loss intervention in producing weight loss in obese patients with poorly controlled asthma.
2. The ultimate purpose is to implement a multi-center weight loss intervention trial for obese patients with poorly controlled asthma.

Conditions

• Asthma

Interventions

BEHAVIORAL

Weight loss intervention

This 6-month intervention will include restricted calorie intake and increased physical activity. Key behavioral strategies to facilitate changes in dietary habits and activity patterns will be introduced, promoted and reinforced throughout the program. Weekly "group meetings" in a synchronous chat (i.e., in real time) led by a facilitator will be the venue for the group process. Extensive web-based resources to support behavior changes will be offered. Group chat sessions will meet online weekly for 6 months.

Sponsors & Collaborators

• American Lung Association

  collaborator OTHER

• National Heart, Lung, and Blood Institute (NHLBI)

  collaborator NIH

• University of Vermont

  collaborator OTHER

• University of Arizona

  collaborator OTHER

• Johns Hopkins University

  lead OTHER

Principal Investigators

• Anne Dixon, MD · University of Vermont

• Robert Wise, MD · Johns Hopkins School of Medicine

• Janet Holbrook, PhD · Johns Hopkins Bloomberg School of Public Health

Study Design

Allocation

NA

Purpose

OTHER

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-11-15

Primary Completion

2020-05-31

Completion

2020-05-31

Countries

• United States

Study Locations