Ruxolitinib + Allogeneic Stem Cell Transplantation in AML
NCT03286530 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 64
Last updated 2026-03-27
Summary
This research study is studying a drug that may help decrease the chances of relapse after Allogeneic Stem Cell transplantation for Acute Myeloid Leukemia. The name of the study drug involved in this study is:
• Ruxolitinib
Conditions
- Acute Myeloid Leukemia
- Acute Myeloid Leukemia in Remission
- Allogeneic Stem Cell Transplantation
Interventions
- DRUG
-
Patients who fulfill eligibility criteria will be entered into the trial to receive Ruxolitinib. After the screening procedures confirm participation in the research study. The participant will be given a drug diary. The participant will be asked to document information in the drug diary about the study treatment.
Sponsors & Collaborators
-
Washington University School of Medicine
collaborator OTHER -
Vanderbilt University
collaborator OTHER -
Ohio State University
collaborator OTHER -
Medical College of Wisconsin
collaborator OTHER -
Massachusetts General Hospital
lead OTHER
Principal Investigators
-
Gabriell Hobbs, MD · Massachusetts General Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 60 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-11-03
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
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