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General Risk Factors and Inflammatory Determinants in Older Patients With Asthma

NCT03278561 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2020-08-14

No results posted yet for this study

Summary

A cross-sectional study in asthma patients to determine if a late age of onset asthma (start symptoms \>18 years old), is associated with more persistent airway/systemic inflammation, worse asthma control, more co-morbidity, a different microbiome and poorer quality of life despite the use of optimized asthma therapy.

Conditions

  • Asthma
  • Late-Onset Asthma
  • Childhood Asthma

Interventions

PROCEDURE

Sputum induction

Sputum induction according to the ERS protocol

PROCEDURE

Blood sample

A blood sample of 100ml will be taken.

Sponsors & Collaborators

  • Gerdien Tramper

    lead OTHER

Principal Investigators

  • GM de Boer, MD · Franciscus Gasthuis Rotterdam

  • GJ Braunstahl, MD, PhD · Franciscus Gasthuis Rotterdam

  • GA Tramper, MD, PhD · Franciscus Gasthuis Rotterdam

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-05-08
Primary Completion
2019-08-31
Completion
2019-12-31

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03278561 on ClinicalTrials.gov