Trial Outcomes & Findings for Use of Negative Pressure Wound Therapy in Morbidly Obese Women After Cesarean Delivery (NCT NCT03269968)

NCT ID: NCT03269968

Last Updated: 2020-10-19

Results Overview

Any of wound infection, seroma/hematoma, wound separation \>1 cm, and wound dehiscence

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

25 participants

Primary outcome timeframe

Four weeks postpartum

Results posted on

2020-10-19

Participant Flow

The study was terminated due to insufficient enrollment. No study data are available.

Participant milestones

Participant milestones
Measure
Negative Pressure Wound Therapy (NPWT)
Women receiving NPWT will have a PREVENA Incision Management Therapy System applied directly onto their skin over the closed incision after delivery. Negative pressure wound therapy (PREVENA Incision Management Therapy System): After cesarean delivery, women in the intervention group will receive PREVENA Incision Management Therapy System.
Standard Dressing
Standard dressing Standard dressing: After cesarean delivery, women in the intervention group will receive standard dressing.
Overall Study
STARTED
0
0
Overall Study
COMPLETED
0
0
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Use of Negative Pressure Wound Therapy in Morbidly Obese Women After Cesarean Delivery

Baseline characteristics by cohort

Baseline data not reported

PRIMARY outcome

Timeframe: Four weeks postpartum

Population: The study was terminated due to insufficient enrollment. No study data are available.

Any of wound infection, seroma/hematoma, wound separation \>1 cm, and wound dehiscence

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Four weeks postpartum

Population: The study was terminated due to insufficient enrollment. No study data are available.

Through patient surveys administered prior to hospital discharge and at four weeks post-operative investigators will evaluate patient satisfaction with wound healing. Satisfactory measures will include how well participants think incision healed mobility after surgery, pain control, and the incision's appearance. Patients were also asked if they had emergency room visits or hospital readmissions. For patients who received NPWT investigators will assess the ease of use, comfort, and perception of its efficacy.

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At time time of admission

Age, race/ethnicity, parity

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At time time of admission

Prepregnancy and at the time of delivery

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At time time of admission

We were unable to adequately recruit for this study. Study was closed.

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At time time of admission

Renal disease, hypertension, diabetes, psychiatric history, sleep apnea, history of venous thromboembolism

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At time time of admission

Gestational diabetes, preeclampsia

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At time time of admission

We were unable to adequately recruit for this study. Study was closed.

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At time time of cesarean delivery

Failed induction, arrest of active phase, arrest of descent, malpresentation, repeat cesarean delivery, desired cesarean

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At the time of admission

Spontaneous labor, rupture of membranes, induction of labor, scheduled cesarean delivery, fetal condition (oligohydroamnios, growth restriction, non reassuring fetal heart tracing)

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At the time of cesarean delivery

We were unable to adequately recruit for this study. Study was closed.

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: Four weeks postpartum

We were unable to adequately recruit for this study. Study was closed.

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At the time of cesarean delivery

We were unable to adequately recruit for this study. Study was closed.

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At the time of cesarean delivery

We were unable to adequately recruit for this study. Study was closed.

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At the time of cesarean delivery

Postpartum hemorrhage, transfusion, ureteral injury, bladder injury, B-lynch suture, and hysterectomy

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At the time of cesarean delivery

We were unable to adequately recruit for this study. Study was closed.

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At the time of cesarean delivery

We were unable to adequately recruit for this study. Study was closed.

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At the time of cesarean delivery

We were unable to adequately recruit for this study. Study was closed.

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At the time of cesarean delivery

We were unable to adequately recruit for this study. Study was closed.

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At the time of cesarean delivery

Cefazolin, Azithromycin, Clindamycin, Gentamicin, and other

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: At the time of cesarean delivery

We were unable to adequately recruit for this study. Study was closed.

Outcome measures

Outcome data not reported

Adverse Events

Negative Pressure Wound Therapy (NPWT)

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Standard Dressing

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Rachael Overcash

MedStar Health Reseach Institute

Phone: 202-877-6093

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place