Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies
NCT03263637 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 44
Last updated 2021-10-22
Summary
The purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and preliminary antitumor activity of AZD4573 in subjects with relapsed or refractory haematological malignancies.
Conditions
- Relapsed or Refractory Haematological Malignancies Including
- Acute Myeloid Leukemia
- Acute Lymphocytic Leukemia
- Chronic Lymphocytic Leukemia
- High Risk Myelodysplastic Syndrome
- Chronic Myelomonocytic Leukemia
- Richter's Syndrome
- B-cell Non-Hodgkin Lymphoma
- T-cell Non-Hodgkin Lymphoma
- Small Lymphocytic Lymphoma
- Multiple Myeloma
Interventions
- DRUG
-
AZD4573
AZD4573 will be administered as a intravenous (IV) infusion.
Sponsors & Collaborators
- lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 130 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-10-24
- Primary Completion
- 2021-09-30
- Completion
- 2021-09-30
Countries
- Germany
- Netherlands
- United Kingdom
Study Locations
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