LTS of Siliq vs. Other Therapies Treating of Adults With Moderate-to-Severe Psoriasis
NCT03254667 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 3500
Last updated 2025-09-16
Summary
Prospective, Observational Study to Assess the Long-Term Safety of Brodalumab Compared with Other Therapies in the Treatment of Adults with Moderate-to-Severe Psoriasis
Conditions
Interventions
- BIOLOGICAL
-
Brodalumab
Brodalumab
- DRUG
-
Comparator Drug (non-biologic IL-17 inhibitors)
Comparator subjects treated with non-biologic IL-17 inhibitors
Sponsors & Collaborators
-
Bausch Health Americas, Inc.
lead INDUSTRY
Principal Investigators
-
Varsha Bhatt · Bausch Health
Eligibility
- Min Age
- 18 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-07-25
- Primary Completion
- 2030-11-10
- Completion
- 2031-11-30
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
A Study of LY3972406 in Adult Participants With Moderate-to-Severe Plaque Psoriasis
NCT06176768 ·Status: COMPLETED ·Phase: PHASE2
-
A Bioequivalence Study Comparing a Single 1.5mL Dose of Brodalumab vs. Two Doses (1.0mL + 0.5mL) of Brodalumab
NCT02173392 ·Status: COMPLETED ·Phase: PHASE1
-
A Real World Study Evaluating the Long-Term Quality of Life of Tildrakizumab in Adult Patients With Psoriasis
NCT03718299 ·Status: COMPLETED ·Phase: PHASE4
-
Study to Evaluate Broadlumab vs Placebo and Ustekinumab
NCT02786732 ·Status: TERMINATED ·Phase: PHASE3
-
An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects
NCT03240809 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
A Study of LY3361237 in Participants With Psoriasis
NCT04975295 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy and Safety of Brodalumab Compared With Placebo and Ustekinumab in Moderate to Severe Plaque Psoriasis Subjects
NCT01708629 ·Status: TERMINATED ·Phase: PHASE3
-
A Phase 3 Study in Participants With Moderate to Severe Psoriasis
NCT01474512 ·Status: COMPLETED ·Phase: PHASE3
-
A Long-term Study to Evaluate Safety and Maintenance of Treatment Effect of LY3074828 in Participants With Moderate-to-Severe Plaque Psoriasis (OASIS-3)
NCT03556202 ·Status: TERMINATED ·Phase: PHASE3
-
Dose Reduction of IL17 and IL23 Inhibitors in Psoriasis
NCT04340076 ·Status: COMPLETED ·Phase: PHASE4
-
Comparing Efficacy and Safety of Bmab 1200 and Stelara in Patients With Moderate to Severe Chronic Plaque Psoriasis
NCT05335356 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Assess the Effects of Switching From a Biologic Treatment to Tildrakizumab Using Patient-reported Outcomes in Adult Participants With Moderate to Severe Plaque Psoriasis
NCT06030076 ·Status: RECRUITING
-
Plaque Psoriasis Efficacy and Safety With Secukinumab
NCT02409667 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Efficacy and Safety/Tolerability of Subcutaneous Tildrakizumab (SCH 900222/MK-3222) in Participants With Moderate-to-Severe Chronic Plaque Psoriasis Followed by a Long-term Extension Study (MK-3222-011)
NCT01729754 ·Status: COMPLETED ·Phase: PHASE3
-
A Study in Participants With Moderate to Severe Psoriasis
NCT01107457 ·Status: COMPLETED ·Phase: PHASE2
-
SEquential Treatment of PSoriasis With Biologics
NCT07187817 ·Status: RECRUITING
-
A Study to Evaluate Clear Skin Effect on Quality of Life in Patients With Plaque Psoriasis.
NCT02752776 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque Psoriasis
NCT02561806 ·Status: COMPLETED ·Phase: PHASE3
-
A Clinical Study of SHR-1314 Injection in the Treatment of Moderate to Severe Plaque Psoriasis in Adults
NCT04121143 ·Status: SUSPENDED ·Phase: PHASE2
-
Efficacy, Safety, and Withdrawal and Retreatment With Brodalumab in Moderate to Severe Plaque Psoriasis Subjects
NCT01708590 ·Status: TERMINATED ·Phase: PHASE3
-
Study to Evaluate Effectiveness and Safety in Subjects With Moderate to Severe Psoriasis
NCT02931838 ·Status: COMPLETED ·Phase: PHASE2
-
Study of the Clinical Activity, Safety, and Tolerability of SRT2104 in Subjects With Moderate to Severe Plaque-Type Psoriasis
NCT01154101 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Tildrakizumab in the Treatment of Scalp Psoriasis
NCT03897088 ·Status: COMPLETED ·Phase: PHASE3
-
Adjusted Brodalumab Dose Compared With Standard Brodalumab Dose in Subjects With Moderate-to-severe Plaque Psoriasis and ≥120 kg Body Weight
NCT04306315 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Subcutaneous Secukinumab in Adults With Moderate to Severe Scalp Psoriasis
NCT02267135 ·Status: COMPLETED ·Phase: PHASE3