Pain Management After TKA: Comparison of Short- and Long-term Nerve Blocks

Summary

The purpose of this study is to determine if there is any significant difference between using a short-term ON-Q nerve block (which is applied prior to surgery and maintained in place until the medication in the initial balls have been fully used, usually 2-4 days) in comparison to a long-term ON-Q nerve block (which is applied prior to surgery and maintained in place up to seven days after surgery). This study will analyze patient reported levels of pain, range of motion, and narcotic use, as well as investigate whether blood loss, blood thinners, and hemoglobin/hematocrit blood levels influence patient pain levels.

This study will compare patient-reported pain, range of motion and narcotic use in total knee arthroplasty patients who receive the short-term and long-term combination nerve block (saphenous and posterior of the adductor canal and wide-field posterior knee.

Conditions

• Anesthesia, Local
• Pain, Postoperative

Interventions

DEVICE

Short-term ON-Q

single port, select-a-flow pump connected to saphenous nerve block catheter until medication in initial balls are depleted (usually 2-4 days)

DEVICE

Short-term ON-Q

single port, fixed flow pump connected to posterior knee catheter until medication in initial balls are depleted (usually 2-4 days)

DRUG

Short-term ON-Q

Bupivacaine 0.125%

DEVICE

Long-term ON-Q

single port, select-a-flow pump connected to saphenous nerve block catheter until day 7 post-operative

DEVICE

Long-term ON-Q

single port, fixed flow pump connected to posterior knee catheter until day 7 post-operative

DRUG

Long-term ON-Q

Bupivacaine 0.125%

Sponsors & Collaborators

• Halyard Health

  collaborator INDUSTRY

• AdventHealth

  lead OTHER

Principal Investigators

• J. Dean Cole, M.D. · AdventHealth

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-09-28

Primary Completion

2019-01-08

Completion

2019-05-20

FDA Device

Yes

Countries

• United States

Study Locations