The Effect of Chimeric Antigen Receptor (CAR)-T Cell Therapy on the Reconstitution of HIV-specific Immune Function
NCT03240328 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2022-09-14
Summary
To study the safety and effectiveness of CAR-T Cell therapy on HIV patients whose plasma HIV has been successfully suppressed after cART, which is expected to enhance the res-constitution of HIV-specific immune function to assist the eradication of HIV reservoir.
Conditions
Interventions
- BIOLOGICAL
-
CAR-T cells
HIV-1 specific chimeric antigen receptor cells
Sponsors & Collaborators
-
Sun Yat-sen University
collaborator OTHER -
Guangzhou 8th People's Hospital
lead OTHER
Principal Investigators
-
Cai Weiping, Bachelor · Guangzhou 8th People's Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-10-04
- Primary Completion
- 2023-12-31
- Completion
- 2030-12-31
Countries
- China
Study Locations
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