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Combination Treatment of 5% Natamycin and 1% Voriconazole in Fungal Keratitis

NCT03230058 · Status: UNKNOWN · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 55

Last updated 2017-07-26

No results posted yet for this study

Summary

OBJECTIVE To evaluate the efficacy and safety of the concurrent treatment of 5% Natamycin and 1% Voriconazole in patients affected by fungal keratitis METHODS AND MATERIALS STUDY POPULATION Patients with smear and or culture proven fungal keratitis presenting to our Instituts, were eligible for enrollment.

STUDY DESIGN Prospective double masked randomized clinical trial.

Conditions

  • Infection, Fungal

Interventions

DRUG

Group 1 Natamycin 5% Suspension + voriconazole 1% eye drops; Group 2 Natamycin 5% Suspension + Vehicle eye drops

instillation of drops

Sponsors & Collaborators

  • L.V. Prasad Eye Institute

    lead OTHER

Principal Investigators

  • merle fernandes, MS · LVPEI

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-01-01
Primary Completion
2018-03-01
Completion
2018-09-30

Countries

  • India

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03230058 on ClinicalTrials.gov