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7-day Compared With 10-day Antibiotic Treatment for Febrile Urinary Tract Infections in Children

NCT03221504 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 221

Last updated 2018-03-20

No results posted yet for this study

Summary

The investigators aim to assess the effectiveness of a 7-day compared with a 10-day course of antibiotic treatment for febrile urinary tract infections (UTIs) in children. It is formulated a hypothesis that a 7-day course of antibiotic therapy is equally effective as a 10-day course of therapy and would entail a lower risk of adverse events and better compliance.

Conditions

  • Urinary Tract Infections in Children

Interventions

OTHER

Longer therapy duration

Patients will receive cefuroxime axetil orally. Treatment will involve the supply of cefuroxime axetil 30 mg/kg/d in two divided doses (in blinded bottles).

OTHER

Shorter therapy duration

Patients will receive placebo orally (in blinded bottles). The volume of the placebo will be like cefuroxime syrup.

Sponsors & Collaborators

  • Medical University of Warsaw

    lead OTHER

Principal Investigators

  • Malgorzata Pańczyk-Tomaszewska, Assistant Professor · Medical Univeristy of Warsaw

  • Maria Daniel, MD · Medical Univeristy of Warsaw

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
3 Months
Max Age
7 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-01-01
Primary Completion
2019-07-31
Completion
2020-01-31

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03221504 on ClinicalTrials.gov