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Femtosecond Laser-assisted Corneal Debridement for Herpes Simplex Keratitis

NCT03217474 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2018-02-22

No results posted yet for this study

Summary

The purpose of the study is to learn if adding femtosecond laser-assisted corneal debridement to a standard therapy of oral ganciclovir can help shorten the healing time of herpes simplex epithelial keratitis (HSK).

Conditions

  • Herpes Simplex Keratitis

Interventions

PROCEDURE

FLDEB

The eye will be anesthetized, and femtosecond laser technology will be used to remove epithelial tissue (diameter: 8mm; depth: 100micron) that includes the loosened diseased corneal epithelial cells. Antibiotic ointments and drops will be instilled postoperatively.

DRUG

Ganciclovir (GCV)

Patient will be treated with GCV orally (200mg, 3 times a day, for 14 days).

DEVICE

Femtosecond laser

A commercial femtosecond laser to create a particular shaped graft for transplantation.

Sponsors & Collaborators

  • Chunxiao Wang

    lead OTHER

Principal Investigators

  • Yizhi Liu, M.D.Ph.D. · Zhongshan Ophthalmic Center, Sun Yat-sen University

  • Ting Huang, M.D.Ph.D. · Zhongshan Ophthalmic Center, Sun Yat-sen University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-07-20
Primary Completion
2018-12-30
Completion
2019-12-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03217474 on ClinicalTrials.gov