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Study of the Effects of Oxytocin on Attentional Bias and Startle in PTSD

NCT03211013 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 17

Last updated 2021-06-10

No results posted yet for this study

Summary

The investigators will test whether intranasal oxytocin (24 IU vs placebo) will induce effects on attention bias and startle comparable to those the investigators have shown to be induced by the presence (vs absence) of a service dog in Veterans diagnosed with PTSD. This possibility is suggested by a 2015 study showing that urinary oxytocin levels are elevated in association with mutual gaze between dogs and their owners.

Conditions

Interventions

DRUG

Oxytocin

single-dose administration of OT nasal spray, complete computer-based tasks post-dose for approximately 1 hour

DRUG

Placebos

single-dose administration of placebo nasal spray, complete computer-based tasks post-dose for approximately 1 hour

Sponsors & Collaborators

  • Palo Alto Veterans Institute for Research

    lead OTHER

Principal Investigators

  • Steven H Woodward, PhD · VA Palo Alto Health Care System

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-07-10
Primary Completion
2021-06-09
Completion
2021-06-09
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03211013 on ClinicalTrials.gov