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Effects of Repeated Doses of Lu AF35700 on Drug Metabolizing Enzymes

NCT03195946 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2018-01-08

No results posted yet for this study

Summary

This study will help determine which types of drugs that may interact with Lu AF35700

Conditions

  • Drug Reactions

Interventions

DRUG

Lu AF35700

tablets for oral use, 10 mg/day

DRUG

Midazolam

syrup for oral use, 4mg/day

DRUG

Cocktail of CYP450 substrates

Caffeine tablets for oral use, 200 mg/day. Omeprazole tablets for oral use, 40 mg/day. Dextromethorphan tablets for oral use, 30 mg/day. Midazolam IV solution for Intravenous use, 0.025 mg/kg/day

Sponsors & Collaborators

  • H. Lundbeck A/S

    lead INDUSTRY

Principal Investigators

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-06-16
Primary Completion
2018-01-03
Completion
2018-01-03

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03195946 on ClinicalTrials.gov