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Clinical Outcome in Patients With Spinal Dural Arteriovenous Fistulas (COPSDAVF)

NCT03192800 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2021-04-22

No results posted yet for this study

Summary

Spinal dural arteriovenous fistulas (SDAVFs) are the most common vascular disorder of the spine and account for approximately 70% of spinal vascular malformation.They are a rare pathology with an excepted incidence of only 5-10 new cases per million inhabitants per year. Most fistulas are found in the thoracolumbar region and \> 80% of all SDAVFs are located between T6 and L2, whereas the cranio-cervical, cervical and sacral fistulas are more rare. SDAVFs have an overwhelmingly male predominance (80%), with an age presentation in the fifth or sixth dacede. It is presumed that SDAVFs are acquired diseases. A typical SDAVF is located inside the dural mater close to nerve root. It is fed by a radiculomeningeal artery and enters a radicular vein that merges in the perimedullary plexus. The presence of a shunt leads to a reversal of blood flow to the spinal cord venous system, which then induces venous hypertensive myelopathy.

Conditions

  • Spinal Vascular Disorder Nos

Sponsors & Collaborators

  • Beijing Haidian Hospital

    collaborator OTHER

  • Hongqi Zhang, MD

    lead OTHER

Principal Investigators

  • Zhang Hongqi, MD.PHD. · Xuanwu Hospital, Beijing

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-03-01
Primary Completion
2023-03-31
Completion
2025-03-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03192800 on ClinicalTrials.gov