Effects of Dapagliflozin in Non-diabetic Patients With Proteinuria
NCT03190694 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 53
Last updated 2024-06-17
Summary
This study tests the hypothesis that dapagliflozin lowers proteinuria in patients with non-diabetic chronic kidney disease.
Conditions
- Chronic Kidney Diseases
- Proteinuria
Interventions
- DRUG
-
Dapagliflozin 10mg
Tablet
Sponsors & Collaborators
- collaborator INDUSTRY
-
Hiddo Lambers Heerspink
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-11-12
- Primary Completion
- 2019-11-01
- Completion
- 2019-12-01
Countries
- Canada
- Malaysia
- Netherlands
Study Locations
More Related Trials
-
Renal Mechanism of Action/Splay vs. TmG
NCT00726505 ·Status: TERMINATED ·Phase: PHASE1
-
GLUcose Transport and REnalPROtection in Chronic Kidney Disease
NCT05998837 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
A Study to Evaluate the Effect of Dapagliflozin on Renal Outcomes and Cardiovascular Mortality in Patients With Chronic Kidney Disease
NCT03036150 ·Status: COMPLETED ·Phase: PHASE3
-
Inhibition of Urinary Angiotensinogen and the Reduction of Blood Pressure by SGLT2 Inhibition in Patients With Type 2 Diabetes
NCT02796170 ·Status: COMPLETED ·Phase: PHASE4
-
Renal Impairment in Type 2 Diabetic Subjects
NCT00554450 ·Status: COMPLETED ·Phase: PHASE1
-
Effects of Dapagliflozin Treatment on Urinary Proteomic Patterns in Patients With Type 2 Diabetes
NCT02914691 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of Dapagliflozin in Chinese Adult Patients With Chronic Kidney Disease
NCT06610526 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Dapagliflozin and Renal Surrogate Outcomes in Advanced Chronic Kidney Disease
NCT05196347 ·Status: COMPLETED ·Phase: PHASE3
-
OPTIMISE-CKD Drug Utilization
NCT05932901 ·Status: COMPLETED
-
Characterization of the Kinetics of Renal Glucose Reabsorption in Response to Dapagliflozin in Healthy Subjects and in Subjects With Type 2 Diabetes Mellitus (T2DM)
NCT01165268 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Dapagliflozin in Non-Diabetic Patients With Nephrotic Syndrome.
NCT05966818 ·Status: UNKNOWN ·Phase: PHASE4
-
A Study to to Assess the Effect of Dapagliflozin When Administered Once a Day Versus Twice a Day on Blood Glucose
NCT01072578 ·Status: COMPLETED ·Phase: PHASE1
-
Vascular Impact of Dapagliflozin in CKD Patients (DAPAVASC)
NCT04930549 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Dapagliflozin on Hepatic and Renal Glucose Metabolism Subjects
NCT02981966 ·Status: COMPLETED ·Phase: PHASE4
-
Renoprotection in Early Diabetic Nephropathy in Pima Indians
NCT00340678 ·Status: COMPLETED ·Phase: PHASE3
-
Decentralized N=1 Study: A Feasible Approach to Evaluate Individual Therapy Response to Dapagliflozin.
NCT06374043 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety in Patients With Type 2 Diabetes Mellitus, Cardiovascular Disease and Hypertension
NCT01031680 ·Status: COMPLETED ·Phase: PHASE3
-
Zibotentan and Dapagliflozin in Patients With Type 2 Diabetes and Elevated Albuminuria
NCT05570305 ·Status: COMPLETED ·Phase: PHASE2
-
Dapagliflozin Treatment in Type 2 Diabetes
NCT04620590 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Low Protein Diet on Top of Dapagliflozin on Chronic Kidney Disease in Patients With Type 2 Diabetes Mellitus
NCT06281899 ·Status: RECRUITING ·Phase: PHASE4
-
Impact of Dapagliflozin in Anemic Chronic Kidney Disease Patients
NCT06897605 ·Status: RECRUITING ·Phase: PHASE2
-
The RENAL LIFECYCLE Trial: A RCT to Assess the Effect of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Severe CKD
NCT05374291 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE3
-
Renoprotective Effects of Dapagliflozin in Type 2 Diabetes
NCT02682563 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Dapagliflozin on Renal Outcomes and Bone Mineral Disease in Non-diabetic Chronic Kidney Disease Patients
NCT05735197 ·Status: COMPLETED ·Phase: PHASE4
-
Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of Ultra Low Doses of Dapagliflozin in Healthy Subjects
NCT01135446 ·Status: COMPLETED ·Phase: PHASE1