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Evaluation of Early Mucosal Healing During Clinical Remission in Pediatric Ulcerative Colitis

NCT03179865 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 28

Last updated 2020-11-03

No results posted yet for this study

Summary

Establishing that mucosal healing (MH) has occurred after therapy is an important treatment goal, and the gold standard is endoscopic evaluation. In UC it is unclear if clinical parameters are adequate. The pediatric ulcerative colitis activity index (PUCAI) has demonstrated good correlations for clinical remission and disease severity, but its role for establishing mucosal healing after therapy has not been validated . The ability to predict mucosal healing may be different for patients in long term remission compared to assessment after obtaining clinical remission. No previous study has prospectively validated the use of PUCAI as a proxy for MH specifically during clinical remission after therapy.

Conditions

Sponsors & Collaborators

  • Wolfson Medical Center

    lead OTHER_GOV

Eligibility

Min Age
4 Years
Max Age
19 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-01-31
Primary Completion
2020-10-31
Completion
2020-11-30

Countries

  • Israel

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03179865 on ClinicalTrials.gov