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Protective Mechanical Ventilation and Risk of Postoperative Complications in Abdominal Surgery

NCT03165760 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2017-05-24

No results posted yet for this study

Summary

Randomized controlled trial, comparing two groups of 40 patients each scheduled for open major abdominal surgery. The intervention group was ventilated with a protective strategy consisting on a low Tidal volume (Vt) (6ml/kg of predicted body weight (PBW)), positive end expiratory pressure (PEEP) = 10 cm H2O and recruitment manoeuvres (RM) after disconnection from the ventilator, the control group had classic ventilation (Vt = 8 ml/kg of PBW, PEEP = 4 cmH2O and no RM).

Conditions

  • Ventilator-Induced Lung Injury
  • Mechanical Ventilation Complication
  • Postoperative Complications

Interventions

PROCEDURE

protective ventilation

the aim of the intervention is to ovoid Ventilator induced lung injury and inflammatory stress

Sponsors & Collaborators

  • Mongi Slim Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-07-01
Primary Completion
2016-12-31
Completion
2016-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03165760 on ClinicalTrials.gov