The Effect and Frequency of Helicobacter Pylori Infection in Primary Immune Thrombocytopenic Patients
NCT03163147 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2017-05-22
Summary
Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by low platelet count (i.e less than 100.000) . In ITP, platelet surface membrane proteins become antigenic for unknown reasons , leading to stimulation of the immune system , autoantibody production, and platelet destruction In recent years ,the list of etiologies of ITP has been steadily increasing, so the term "idiopathic" is becoming obsolete, increasingly replaced by "immune"TP .
Treatment of ITP may be conceptually divided into rescue therapy and maintenance therapy . the terminology of corticosteroid-dependence means The need for ongoing or repeated doses administration of corticosteroids for at least 2 months to maintain a platelet count at or above 30 \_ 109/L and/or to avoid bleeding. So, patients with corticosteroid dependence are considered non responders
Conditions
- Effects Toxics
Sponsors & Collaborators
-
Assiut University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-06-01
- Primary Completion
- 2018-06-01
- Completion
- 2018-06-01
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