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Mapping the Human HIV Chronobiome

NCT03133559 · Status: SUSPENDED · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2026-02-24

No results posted yet for this study

Summary

Individuals infected with HIV have a high risk of developing metabolic comorbidities not traditionally associated with the immune dysregulation and deficiency associated with HIV infection and AIDS. Many of these comorbidities in HIV uninfected individuals have been linked to a disordered circadian clock function. The study investigators will further evaluate the circadian clock in HIV infection as a mechanism underlying the metabolic dysregulation in this population.

Conditions

Interventions

OTHER

Observational

We will use a deep phenotyping approach to collect multidimensional datasets from individuals infected with HIV compared to healthy controls to define circadian rhythm disruptions associated with HIV infection.

Sponsors & Collaborators

Principal Investigators

  • Carsten Skarke, MD · University of Pennsylvania

Eligibility

Min Age
25 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-04-19
Primary Completion
2028-02-29
Completion
2029-08-31

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03133559 on ClinicalTrials.gov