Effect of Solanum Melongena Extract in the Treatment of Arsenical Skin Lesion
NCT03127670 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2018-07-13
Summary
Solanum melongena is a common vegetable contains phytochemicals which prevent, reduce or delay the oxidation of DNA and alter the cellular signal transduction pathways controlling cell proliferation and apoptosis of human cancer. The skin of Solanum melongena peel contains nasunin an anthocyanins and chlorogenic acid which have anti-inflammatory, antioxidant, antimutagenic and antiangiogenic properties. Extract of Solanum melongena is used in actinic keratosis and Squamous cell carcinoma of the skin. This study will determine any change in arsenical skin lesion after administrating Solanum melongena extract cream.
Conditions
- Arsenical Keratosis
Interventions
- DRUG
-
Solanum melongena peel extract 0.05%
Administered topically twice daily for 12 weeks
Sponsors & Collaborators
-
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
lead OTHER
Principal Investigators
-
Mir Misbahuddin, PhD · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-11-14
- Primary Completion
- 2017-12-31
- Completion
- 2017-12-31
Countries
- Bangladesh
Study Locations
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