Interventions for Postoperative Delirium: Biomarker-3

NCT03124303 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 468

Last updated 2025-12-15

No results posted yet for this study

Summary

The IPOD-B3 study aims to characterize the relationship between premorbid brain activity and postoperative delirium in patients undergoing major surgery. This is a expansion of the NeuroVISION Bolt-On study, NCT01980511.

Conditions

  • Delirium

Interventions

PROCEDURE

High Density-Electroencephalogram

EEG is a safe non-invasive technology without complications that may be used to help diagnose delirium

PROCEDURE

Magnetic Resonance Imaging

MRI scan of brain

PROCEDURE

Blood specimen collection

Blood will be collected from participants

DIAGNOSTIC_TEST

Pupillometry

A pupillometer is a device that measures the size of the pupils.

Sponsors & Collaborators

  • National Institute on Aging (NIA)

    collaborator NIH
  • University of Wisconsin, Madison

    lead OTHER

Principal Investigators

  • Robert Pearce, MD, PhD · University of Wisconsin, Madison

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-02-13
Primary Completion
2029-12-31
Completion
2029-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03124303 on ClinicalTrials.gov