Prospective Cohort for Adult Hemophagocytosis
NCT03117010 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 81
Last updated 2026-04-24
Summary
This prospective study enrolls subjects who have clinical and laboratory manifestations related with hemophagocytic lymphohistiocytosis. The purpose of the study is to evaluate clinical and biological features of adult hemophagocytic lymphohistiocytosis. The enrolled subjects into this study will be evaluated according to the HLH (hemophagocytic lymphohistiocytosis)criteria and treated with systemic immunosuppressive therapy or chemotherapy. All subjects will be regularly monitored by physicians participating in this study.
Conditions
- Hemophagocytic Lymphohistiocytoses
Interventions
- DRUG
-
Steroids
High dose dexamethasone 20 mg PO or IV
- DRUG
-
Etoposide
Etoposide 150mg/BSA
Sponsors & Collaborators
-
Samsung Medical Center
lead OTHER
Principal Investigators
-
Seok Jin Kim, MD, PhD · Samsung Medical Center
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-01-01
- Primary Completion
- 2028-12-31
- Completion
- 2028-12-31
Countries
- South Korea
Study Locations
More Related Trials
-
The Tolerability,Safety,PK/PD Study of rhTPO in the Patients With Liver Function Impairment
NCT03673215 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
The Prospective Randomized Controlled Study of Eltrombopag on Hematopoietic Reconstruction After Allogeneic HSCT
NCT03902041 ·Status: UNKNOWN
-
Baricitinib for Steroid-resistant/Relapse Immune Thrombocytopenia
NCT05446831 ·Status: UNKNOWN ·Phase: PHASE2
-
Efficacy and Safety of Hetrombopag in Non-severe Aplastic Anemia
NCT05018936 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
An Observational, Multicenter Study to Evaluate the Safety and Effectiveness of Hetrombopag in Patients With ITP or AA
NCT05333861 ·Status: NOT_YET_RECRUITING
-
Role of Eltrombopag as First Line Therapy in Primary Immune Thrombocytopenia.
NCT06531018 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
The Investigate Efficacy and Safety Evaluation of Bortezomib in Patients With Relapsed/Refractory Immune Thrombocytopenia
NCT05599880 ·Status: RECRUITING ·Phase: PHASE2
-
GTP Regimen in the Treatment of Refractory/Recurrent HLH
NCT06038422 ·Status: UNKNOWN ·Phase: PHASE3
-
Eltrombopag Phase III Study In Chinese Chronic ITP Patients
NCT01762761 ·Status: COMPLETED ·Phase: PHASE3
-
Eltrombopag in Patients With Delayed Post Transplant Thrombocytopenia.
NCT01791101 ·Status: COMPLETED ·Phase: PHASE2
-
Eltrombopag Plus Diacerein vs Eltrombopag in Adult ITP
NCT04917679 ·Status: COMPLETED ·Phase: PHASE2
-
Gut Microbiota in ITP
NCT05118126 ·Status: UNKNOWN
-
Subcutaneous Daratumumab Administration in the Thigh Vs Abdomen in Plasma Cell Disorders
NCT07075510 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Evaluating the Efficacy and Safety of QL0911 in the Prevention of Chemotherapy- Induced Thrombocytopenia
NCT05554913 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Study of Efficacy and Safety of Eltrombopag in Lower-risk MDS Patients With Platelet Transfusion Dependence
NCT04797000 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of Switching Avatrombopag and Rh-TPO in ITP
NCT04913597 ·Status: UNKNOWN
-
Avatrombopag to Promote Platelet Engraftment After Allo-HSCT
NCT05143892 ·Status: UNKNOWN ·Phase: PHASE2
-
Efficacy and Safety of Eltrombopag + Tacrolimus in Chinese Refractory or Relapsed Aplastic Anemia Patients
NCT04403321 ·Status: COMPLETED ·Phase: PHASE2
-
An Investigation of rhTPO With Different Frequencies in the Management of ITP
NCT02139501 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Evaluate the Efficacy and Safety of Oral Rilzabrutinib in Adults With Immune Thrombocytopenia (ITP) Who Failed First-line Treatment
NCT07007962 ·Status: RECRUITING ·Phase: PHASE3
-
Sequential rhTPO and Eltrombopag Following Glucocorticoids for Severe Adult ITP
NCT07189910 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
An Observational Study to Evaluate the Efficacy of Biweekly Romiplostim in Adult Patients With ITP
NCT02338414 ·Status: UNKNOWN ·Phase: PHASE2
-
Lusutrombopag in the Treatment of Immune Thrombocytopenia (ITP)
NCT06287567 ·Status: COMPLETED ·Phase: PHASE2
-
Iguratimod Plus Low-dose Rituximab vs Low-dose Rituximab in Corticosteroid-resistant or Relapsed ITP
NCT07057778 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
High-dose Dexamethasone Plus Hetrombopag vs High-dose Dexamethasone Alone as Frontline Treatment for Newly Diagnosed Adult Primary Immune Thrombocytopenia: A Prospective, Multicenter, Randomized Trial
NCT05943691 ·Status: UNKNOWN ·Phase: PHASE2