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Postoperative Pain Alleviation in Open Heart Surgery

NCT03106818 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2017-11-22

No results posted yet for this study

Summary

Effective pain relief after cardiac surgery has assumed importance with the introduction of fast track discharge protocols that requires early weaning from mechanical ventilation. Inadequate pain control reduces the capacity to cough, mobility, increases the frequency of atelectasis, and prolongs recovery. Infiltration of local anesthetics near the surgical wound has shown to improve early postoperative pain in various surgical procedures.

Magnesium is the fourth most plentiful cation in our body. It has antinociceptive effects in animal and human models of pain.

Conditions

  • Open Heart Surgery
  • Postoperative Pain

Interventions

DRUG

bupivacain with magnesium sulphate

will receive bupivacain 0.125% and magnesium sulphate 5% infusion in the presternum , for 48 hours

DRUG

Bupivacaine only

will receive bupivacain 0.125% infusion in the presternum , for 48 hours

DRUG

conventional

only conventional post operative analgesics will be used

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Emad Kamel Said, MD · Anesthesia departement , Faculty of Medicine , Assiut university

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-07-31
Primary Completion
2017-03-31
Completion
2017-07-31

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03106818 on ClinicalTrials.gov