MedTrace Logo

Heart Rate Variability Under Propofol and Sevoflurane

NCT03098875 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2017-04-04

No results posted yet for this study

Summary

Patients were randomized into 2 groups according to the anesthetic, propofol or sevoflurane. Induction and maintenance were standardized, and after the end of surgery, two steady-state recordings were performed at BIS 25 and BIS 55. Bispectral Index and ECG were continuously recorded and cardiac autonomic nervous activity was investigated using spectral analysis of RR Interval variability

Conditions

  • General Anesthesia

Interventions

DRUG

Sevoflurane

General anesthesia using sevoflurane as a hypnotic agent

DRUG

Propofol

General anesthesia using propofol as a hypnotic agent

DRUG

Remifentanil

General anesthesia using remifentanil as an analgesic.

Sponsors & Collaborators

  • Hôpital Armand Trousseau

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
13 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-01-31
Primary Completion
2009-12-31
Completion
2010-09-30

Countries

  • France

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03098875 on ClinicalTrials.gov