Impact of EDUcation Strategy on Patients With COLorectal CANCER or Advanced Adenoma in the Detection of Colorectal Cancer of Their First-degree Relatives

Summary

The relative risk of colorectal cancer (CRC) is increased in first-degree relatives of patients with CRC or advanced adenoma. In the high-risk CCR population defined by a family history at the first stage of CRC or advanced adenoma before age 60, total colonoscopy is the recommended screening test. In France, the rate of screening colonoscopy in this population at high risk of CRC is insufficient, which limits the effectiveness of this targeted screening.

The main reason for this low participation rate is that most patients undergoing RCC or advanced adenoma are unaware of the family implications of their diagnosis and therefore reluctant to disseminate this information to their patients Related matters. The need for a better perception of the personal risk of CRC in first-degree relatives of patients with CRC or advanced adenoma, with the expected coronary adherence to increasing screening, requires a good understanding of risk through Clear, adapted and comprehensible information that can be relayed personally by the case-index.

The objective of this project is to develop a personalized prevention and screening program for the JRC in order to meet the needs of the relatives of the sick. The means of intervention that will be implemented respond to the need to better take into account the level of CRC risk in a family-based CRC screening and prevention approach adapted to a high-risk CRC group characterized by Family history at the first stage of CRC or advanced adenoma and, consequently, to improve the information of the subjects concerned by screening and prevention of CRC.

The aim of the case-index education is to induce its intervention with its relatives to promote CCR screening. The use of the index case, as a means of providing information to relatives, implies an educational and psychological approach, based on evidence, but adapted and personalized.

Conditions

• Cancer Colorectal

Interventions

BEHAVIORAL

Therapeutic Education Strategy

In the experimental arm of the study ("intervention group"), a screening information and education system will be implemented. The particularities of the index cases likely to require an adaptation of the device will be collected, analyzed and taken into account (level of health literacy, socio-economic status, level of education, professional activity ...). The analysis and intervention frameworks derived from theories on health behaviors will be mobilized (theory of reasoned action, theory of planned behaviors) and applied in order to reinforce the "intention" of the target audience. The analysis and intervention frameworks resulting from the educational sciences will be integrated with a "competence" approach (Aizen, 1991, Denovel, Dufour, Prochaska, 1983, Le Boterf, 2002).

Sponsors & Collaborators

• University Hospital, Angers

  collaborator OTHER_GOV

• Nantes University Hospital

  collaborator OTHER

• Centre Hospitalier de Dreux

  collaborator OTHER

• Hospital BLOIS

  collaborator UNKNOWN

• Hospital LOCHES

  collaborator UNKNOWN

• Poitiers University Hospital

  collaborator OTHER

• UNIVERSITY HOSPITAL, ORLEANS

  collaborator UNKNOWN

• Clinic LE MANS

  collaborator UNKNOWN

• University Hospital, Tours

  lead OTHER

Principal Investigators

• CAROLI BOSC Françis- Xavier, Pr · University Hospital, Angers

• MATYSIAK-BUDNIK Tamara, Pr · Nantes University Hospital

• LANDAU Alain, Dr · CHG DREUX

• GARGOT Denis, Dr · CHG BLOIS

• BARBIEUX Jean- Pierre, Dr · CHG LOCHES

• TOUGERON David, Pr · CHU Poitiers

• LEGOUX Jean- Louis, Dr · CHR ORLEANS

• BOURGEOIS Hugues, Dr · Clinic Victor Hugo LE MANS

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

40 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-04-10

Primary Completion

2019-01-19

Completion

2019-01-19

Countries

• France

Study Locations