Validation of a Risk Score Opportunistic Infections Development in Kidney Transplant Patients

Summary

This study validate the usefulness of SIMPLICITY score to characterize the immune status of the kidney transplant receiver at two points along its course (the one and six months after transplantation), by determination in peripheral blood of various parameters related to cellular immunity (count subpopulations of CD3+ (cluster of differentiation 3), CD4+ (cluster of differentiation 4) and CD8+( cluster of differentiation 8)), humoral immunity (immunoglobulins count) and innate (complement).

Conditions

• Opportunistic Infections

Sponsors & Collaborators

• Roche Farma, S.A

  collaborator INDUSTRY

• Sociedad Española de Trasplante

  lead OTHER

Principal Investigators

• José María Aguado, MD · Hospital Universitario 12 de Octubre

• Daniel Serón, MD · Hospital Universitario Vall d´Hebrón

• Ángel Alonso, MD · Hospital Universitario de A Coruña

• Domingo Hernández Marrero, MD · Hospital Carlos Haya

• Álex Gutiérrez Dalmau, MD · Hospital Miguel Servet

• Roberto Gallego, MD · Hospital Dr. Negrín

• Juan Carlos Ruiz, MD · Hospital Marqués de Valdecilla

• Frederic Cofàn, MD · Hospital Clinic of Barcelona

• José M Cruzado, MD · Hospital Universitari de Bellvitge

• Daniel Serón, MD · Hospital Universitario Vall d´Hebrón

• María José Pérez Sáez, MD · Hospital del Mar

• Miguel Angel Muñoz Cepeda, MD · Hospital Virgen de la Salud

• Ángel Alonso, MD · Hospital Universitario de A Coruña

• Gonzalo Gómez, MD · Hospital Son Espases

• Amado Andrés, MD · Hospital Universitario 12 de Octubre

• José Mª Portolés, MD · Hospital Universitario Puerta de Hierro Majadahonda

• Roberto Marcén, MD · Hospital Universitario Ramon y Cajal

• Luisa Jimeno Garcia, MD · Hospital Virgen de la Arrixaca

• Luis M Pallardó Mateu, MD · Hospital Dr. Peset

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-08-31

Primary Completion

2017-02-15

Completion

2017-02-15

Countries

• Spain

Study Locations