Immunotherapy and Irreversible Electroporation in the Treatment of Advanced Pancreatic Adenocarcinoma
NCT03080974 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2025-10-29
Summary
Compare the efficacy and tolerability of irreversible electroporation in combination with Nivolumab in patients with locally advanced pancreatic cancer.
Conditions
- Pancreatic Adenocarcinoma
Interventions
- DRUG
-
Given post-operatively every two weeks for a total of 4 doses. Dose based on weight.
- PROCEDURE
-
Irreversible Electroporation
Non-thermal ablation of tumor
Sponsors & Collaborators
-
University of Louisville
lead OTHER
Principal Investigators
-
Robert Martin, MD, PhD · University of Louisville
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-08-14
- Primary Completion
- 2028-06-01
- Completion
- 2029-04-01
- FDA Drug
- Yes
Countries
- United States
Study Locations
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