Trial Outcomes & Findings for Evaluation of X-ray, Acetabular Guides and CT in THR (NCT NCT03072706)

NCT ID: NCT03072706

Last Updated: 2026-02-24

Results Overview

The difference between planned and achieved acetabular cup anteversion assessed by post-operative CT scan

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

54 participants

Primary outcome timeframe

6 weeks (+/- 2 weeks) post-surgery

Results posted on

2026-02-24

Participant Flow

Participant milestones

Participant milestones
Measure
Standard Group
2D X-ray templating technology 2D X-ray templating technology: Standard care where hip replacement is planned using 2D X-ray templating software
Corin OPS™
Corin Optimised Positioning System (OPS) Dynamic Hip Analysis Corin OPS™: The OPS Dynamic Hip Analysis is a computer software package used to generate simulations of a total joint replacement from patient imaging. The dynamic simulation is used for operative planning, including implant selection, sizing and placement; and to create custom instruments or delivery specifications referencing the patient's anatomy and bio-mechanics. The simulation can also be used for the post-operative evaluation of joint performance.
Overall Study
STARTED
27
27
Overall Study
COMPLETED
25
26
Overall Study
NOT COMPLETED
2
1

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Evaluation of X-ray, Acetabular Guides and CT in THR

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Standard Group
n=27 Participants
2D X-ray templating technology 2D X-ray templating technology: Standard care where hip replacement is planned using 2D X-ray templating software
Corin OPS™
n=27 Participants
Corin Optimised Positioning System (OPS) Dynamic Hip Analysis Corin OPS™: The OPS Dynamic Hip Analysis is a computer software package used to generate simulations of a total joint replacement from patient imaging. The dynamic simulation is used for operative planning, including implant selection, sizing and placement; and to create custom instruments or delivery specifications referencing the patient's anatomy and bio-mechanics. The simulation can also be used for the post-operative evaluation of joint performance.
Total
n=54 Participants
Total of all reporting groups
Age, Continuous
57.3 years
STANDARD_DEVIATION 9.8 • n=58 Participants
58.8 years
STANDARD_DEVIATION 7.4
58.1 years
STANDARD_DEVIATION 8.6 • n=1 Participants
Sex: Female, Male
Female
12 Participants
n=58 Participants
18 Participants
30 Participants
n=1 Participants
Sex: Female, Male
Male
15 Participants
n=58 Participants
9 Participants
24 Participants
n=1 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=58 Participants
0 Participants
0 Participants
n=1 Participants
Race (NIH/OMB)
Asian
0 Participants
n=58 Participants
0 Participants
0 Participants
n=1 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=58 Participants
0 Participants
0 Participants
n=1 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=58 Participants
0 Participants
0 Participants
n=1 Participants
Race (NIH/OMB)
White
24 Participants
n=58 Participants
23 Participants
47 Participants
n=1 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=58 Participants
0 Participants
0 Participants
n=1 Participants
Race (NIH/OMB)
Unknown or Not Reported
3 Participants
n=58 Participants
4 Participants
7 Participants
n=1 Participants
Region of Enrollment
United Kingdom
27 participants
n=58 Participants
27 participants
54 participants
n=1 Participants
BMI
29.7 kg/m2
STANDARD_DEVIATION 5.0 • n=58 Participants
30.3 kg/m2
STANDARD_DEVIATION 4.8
30.0 kg/m2
STANDARD_DEVIATION 4.9 • n=1 Participants

PRIMARY outcome

Timeframe: 6 weeks (+/- 2 weeks) post-surgery

The difference between planned and achieved acetabular cup anteversion assessed by post-operative CT scan

Outcome measures

Outcome measures
Measure
Standard Group
n=27 Participants
2D X-ray templating technology 2D X-ray templating technology: Standard care where hip replacement is planned using 2D X-ray templating software
Corin OPS™
n=27 Participants
Corin Optimised Positioning System (OPS) Dynamic Hip Analysis Corin OPS™: The OPS Dynamic Hip Analysis is a computer software package used to generate simulations of a total joint replacement from patient imaging. The dynamic simulation is used for operative planning, including implant selection, sizing and placement; and to create custom instruments or delivery specifications referencing the patient's anatomy and bio-mechanics. The simulation can also be used for the post-operative evaluation of joint performance.
Acetabular Cup Anteversion Angle
5.8 degree
Standard Deviation 5.8
3.7 degree
Standard Deviation 2.9

Adverse Events

Standard Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Corin OPS™

Serious events: 1 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Serious adverse events
Measure
Standard Group
n=27 participants at risk
2D X-ray templating technology 2D X-ray templating technology: Standard care where hip replacement is planned using 2D X-ray templating software
Corin OPS™
n=27 participants at risk
Corin Optimised Positioning System (OPS) Dynamic Hip Analysis Corin OPS™: The OPS Dynamic Hip Analysis is a computer software package used to generate simulations of a total joint replacement from patient imaging. The dynamic simulation is used for operative planning, including implant selection, sizing and placement; and to create custom instruments or delivery specifications referencing the patient's anatomy and bio-mechanics. The simulation can also be used for the post-operative evaluation of joint performance.
Hepatobiliary disorders
Cholecystitis
0.00%
0/27 • From consent to the last follow-up visit at 12 months.
3.7%
1/27 • Number of events 2 • From consent to the last follow-up visit at 12 months.

Other adverse events

Adverse event data not reported

Additional Information

Professor Richard King

University Hospitals Coventry and Warwickshire NHS Trust

Phone: 02476 965065

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place